Physical Therapy For Internal Medicine Department, Faculty of Physical Therapy, Beni-Suef University, Ben-Suef, Egypt.
Basic Sciences Department, Faculty of Physical Therapy, Beni-Suef University, Ben-Suef, Egypt.
J Rehabil Med. 2024 Jun 11;56:jrm25491. doi: 10.2340/jrm.v56.25491.
To assess the clinical effects of incentive spirometry (IS) and diaphragmatic breathing (DB) in patients with post COVID-19 condition and diaphragmatic dysfunction as compared with the standard care alone.
The present longitudinal randomized study included 60 patients with post COVID-19 condition and diaphragmatic dysfunction. Patients were equally randomized to receive standard care plus IS (G1), standard care plus DB (G2) or standard care alone (G3) for 8 weeks. The primary outcome is clinical improvement as evaluated by the modified Medical Research Council (mMRC) dyspnoea scale.
Comparison between the studied groups revealed significant improvement in G1 and G2 in all parameters at the end of follow-up. However, no significant improvement was found in G3. At the end of follow-up, 15 patients (75.0%) in G1, 11 patients (55.0%) in G2, and 3 patients (15.0%) in G3 showed improvement on the mMRC dyspnoea scale. Multivariate logistic regression analysis identified mild acute COVID-19 infection (p = 0.009), use of IS (p < 0.001), and use of DB (p = 0.023) as significant predictors of improvement on the mMRC dyspnoea scale.
IS or DB training in addition to the standard care in post COVID-19 condition was associated with better clinical improvement as compared with the standard care alone.
评估激励式呼吸训练（IS）和膈式呼吸（DB）在新冠后状态合并膈肌无力患者中的临床效果，与单独标准治疗相比。
本前瞻性随机研究纳入 60 例新冠后状态合并膈肌无力患者。患者等分为三组，分别接受标准治疗+IS（G1）、标准治疗+DB（G2）或单独标准治疗（G3），治疗 8 周。主要结局为改良呼吸困难量表（mMRC）评估的临床改善情况。
组间比较显示，G1 和 G2 在随访结束时所有参数均有显著改善，但 G3 无显著改善。随访结束时，G1 组 15 例（75.0%）、G2 组 11 例（55.0%）、G3 组 3 例（15.0%）的 mMRC 呼吸困难量表评分改善。多变量逻辑回归分析发现，轻度急性新冠感染（p=0.009）、使用 IS（p<0.001）和使用 DB（p=0.023）是 mMRC 呼吸困难量表评分改善的显著预测因素。
与单独标准治疗相比，新冠后状态患者在标准治疗基础上联合 IS 或 DB 训练可获得更好的临床改善。
