The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China.
J Tradit Chin Med. 2019 Feb;39(1):103-110.
To observe the effect of acupuncture or electroacupuncture (EA) combined with usual medical care for treating knee osteoarthritis (KOA) .
A total of 90 patients with KOA were randomly allocated to 3 groups: usual care group (UC group, n = 30) was treated by pharmacological treatment of non-steroidal anti-inflammatory drugs (NSAIDs) and drugs for activating blood circulation (Ds-ABC), acupuncture (AP) combined with usual care group (UC group) (AP + UC group, n = 30) and EA combined with UC group (EA + UC group, n = 30). The primary outcome measurements included pain visual analogue scale/score (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC Index) and its subscales. Secondary outcome measurement was Assessment of Quality of Life instrument version of the 36-item Short Form Health Survey (AQoL-SF36).
By the end of the 1st week, AP + UC group and EA + UC group exhibited statistically significant improvements in primary outcome measures, except for WOMAC stiffness, compared with the UC group (P < 0.05). Moreover, the energy/fatigue domain of AQoL-SF36 in the AP + UC group showed better results than UC group (P < 0.05). By the end of the 2nd week, all the primary outcome measures revealed that either the AP + UC or EA + UC group demonstrating remarkable advantages compared with the UC group (P < 0.05). The social functioning and general health domains of AQoL-SF36 in the two acupuncture-intervention groups were improved significantly than UC group (P < 0.05). We also found the energy/fatigue and emotional wellbeing domains of AQoL-SF36 in the EA + UC group demonstrated better results than UC group (P < 0.05).
AP or EA combined with usual care is more effective than usual care alone for the treatment of KOA, the intervention of electric current in the process of acupuncture may improve more domains of AQoL-SF36 in KOA patients.
观察针刺或电针(EA)联合常规医疗治疗膝骨关节炎(KOA)的效果。
共 90 例 KOA 患者随机分为 3 组:常规治疗组(UC 组,n = 30)给予非甾体抗炎药(NSAIDs)和活血化瘀药物(Ds-ABC)的药物治疗,针刺(AP)联合常规治疗组(AP + UC 组,n = 30)和 EA 联合 UC 组(EA + UC 组,n = 30)。主要结局测量包括疼痛视觉模拟量表/评分(VAS)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC 指数)及其子量表。次要结局测量是 36 项简短健康调查问卷版本的生活质量评估工具(AQoL-SF36)。
第 1 周结束时,AP + UC 组和 EA + UC 组除 WOMAC 僵硬外,主要结局指标均较 UC 组有统计学意义的改善(P < 0.05)。此外,AP + UC 组的 AQoL-SF36 能量/疲劳域的结果优于 UC 组(P < 0.05)。第 2 周结束时,AP + UC 组或 EA + UC 组的所有主要结局指标均较 UC 组有显著优势(P < 0.05)。在两个针刺干预组中,AQoL-SF36 的社会功能和一般健康领域也有显著改善,优于 UC 组(P < 0.05)。我们还发现,在 EA + UC 组中,AQoL-SF36 的能量/疲劳和情绪健康领域的结果优于 UC 组(P < 0.05)。
针刺或电针联合常规护理治疗 KOA 比单纯常规护理更有效,针刺过程中的电流干预可能会改善 KOA 患者 AQoL-SF36 的更多领域。