富含中链脂肪酸的三酰甘油：人乳和婴儿配方奶在消化过程中脂肪分解的比较。
Triacylglycerol Containing Medium-Chain Fatty Acids: Comparison of Human Milk and Infant Formulas on Lipolysis during Digestion.
机构信息
State Key Lab of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
International Joint Research Laboratory for Lipid Nutrition and Safety, Collaborative Innovation Centre of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.
出版信息
J Agric Food Chem. 2020 Apr 8;68(14):4187-4195. doi: 10.1021/acs.jafc.9b07481. Epub 2020 Mar 30.
Medium-chain triacylglycerol (MCT) is widely used in infant formulas (IFs) to provide medium-chain fatty acids (MCFAs) for infants with special fat absorption requirements. However, MCFAs naturally present in human milk are medium-and long-chain triacylglycerols (MLCTs). This study investigated the effect of triacylglycerol containing MCFAs (MLCT MCT) on lipolysis by comparison of human milk and IFs containing 0, 20, 30, and 55% of MCT (IF 1 to IF 4) using an digestion model. Rabbit gastric lipase showed an extent of digestion within the expected range, and was selected as the alternative to human gastric lipase. All IFs showed a lower lipolysis degree compared with human milk. There was no significant difference ( = 0.175) among IFs supplemented with MCT at the end of intestinal digestion. In addition, the digestion of IFs with different MCT contents led to different free fatty acid profiles, which may have health effects on infants.
中链三酰甘油（MCT）广泛应用于婴儿配方奶粉（IFs）中，为有特殊脂肪吸收需求的婴儿提供中链脂肪酸（MCFAs）。然而，母乳中天然存在的 MCFAs 是中长链三酰甘油（MLCTs）。本研究通过使用消化模型，比较了含有 0、20、30 和 55%MCT（IF1 至 IF4）的人乳和 IFs，研究了含有 MCFAs 的三酰甘油（MLCT-MCT）对脂肪分解的影响。兔胃脂肪酶的消化程度在预期范围内，被选为替代人胃脂肪酶的选择。与人乳相比，所有 IFs 的脂肪分解程度都较低。在肠消化结束时，添加 MCT 的 IFs 之间没有显著差异（=0.175）。此外，不同 MCT 含量的 IFs 的消化导致不同的游离脂肪酸谱，这可能对婴儿的健康有影响。
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