Assistance Publique - Hôpitaux de Paris, Service de Chirurgie Maxillo-faciale et Stomatologie, Hôpital Universitaire Pitié-Salpêtrière, Université Pierre et Marie Curie Paris 6, Sorbonne Université, 75013 Paris, France.
Assistance Publique - Hôpitaux de Paris, Service des Maladies Infectieuses et Tropicales, Hôpital Universitaire Pitié-Salpêtrière, Sorbonne Université, 75013 Paris, France.
Parasite. 2020;27:16. doi: 10.1051/parasite/2020015. Epub 2020 Mar 18.
We report an autochthonous case of oral dirofilariasis in a 46-year-old female patient exposed in South-Eastern France. The patient first presented eyelid creeping dermatitis of one-week duration, then a sub-mucosal nodule appeared in the cheek. The entire nodule was removed surgically. Histologically, the nodule appeared as inflammatory tissue in which a worm was seen. The molecular analysis, based on cox1 and 12S sequences, identified Dirofilaria repens. Ivermectin treatment was given prior to diagnosis, while taking into consideration the most common causes of creeping dermatitis, but treatment was ineffective. The oral form of dirofilariasis is uncommon and could lead to diagnostic wandering.
我们报告了一例在法国东南部暴露的 46 岁女性口腔犬恶丝虫病的本土病例。患者最初表现为为期一周的眼睑爬行性皮炎，然后脸颊出现粘膜下结节。整个结节通过手术切除。组织学上，结节表现为炎症组织，其中可见一条虫。基于 cox1 和 12S 序列的分子分析鉴定为犬恶丝虫。在诊断前给予伊维菌素治疗，同时考虑了爬行性皮炎最常见的病因，但治疗无效。口腔犬恶丝虫病并不常见，可能导致诊断困难。
