Higgins Diana M, Buta Eugenia, Heapy Alicia A, Driscoll Mary A, Kerns Robert D, Masheb Robin, Becker William C, Hausmann Leslie R M, Bair Matthew J, Wandner Laura, Janke E Amy, Brandt Cynthia A, Goulet Joseph L
Anesthesiology, Critical Care, and Pain Medicine Service, VA Boston Healthcare System, Boston, Massachusetts.
Boston University School of Medicine, Boston, Massachusetts.
Pain Med. 2020 Oct 1;21(10):2563-2572. doi: 10.1093/pm/pnaa043.
To examine the relationship between body mass index (BMI) and pain intensity among veterans with musculoskeletal disorder diagnoses (MSDs; nontraumatic joint disorder; osteoarthritis; low back, back, and neck pain).
Administrative and electronic health record data from the Veterans Health Administration (VHA).
A national cohort of US military veterans with MSDs in VHA care during 2001-2012 (N = 1,759,338).
These cross-sectional data were analyzed using hurdle negative binomial models of pain intensity as a function of BMI, adjusted for comorbidities and demographics.
The sample had a mean age of 59.4, 95% were male, 77% were white/Non-Hispanic, 79% were overweight or obese, and 42% reported no pain at index MSD diagnosis. Overall, there was a J-shaped relationship between BMI and pain (nadir = 27 kg/m2), with the severely obese (BMI ≥ 40 kg/m2) being most likely to report any pain (OR vs normal weight = 1.23, 95% confidence interval = 1.21-1.26). The association between BMI and pain varied by MSD, with a stronger relationship in the osteoarthritis group and a less pronounced relationship in the back and low back pain groups.
There was a high prevalence of overweight/obesity among veterans with MSD. High levels of BMI (>27 kg/m2) were associated with increased odds of pain, most markedly among veterans with osteoarthritis.
研究患有肌肉骨骼疾病诊断(MSDs;非创伤性关节疾病;骨关节炎;腰、背和颈部疼痛)的退伍军人中体重指数(BMI)与疼痛强度之间的关系。
退伍军人健康管理局(VHA)的行政和电子健康记录数据。
2001 - 2012年期间在VHA接受治疗的患有MSDs的美国退伍军人全国队列(N = 1,759,338)。
使用疼痛强度的障碍负二项式模型分析这些横断面数据,该模型将疼痛强度作为BMI的函数,并对合并症和人口统计学因素进行了调整。
样本的平均年龄为59.4岁,95%为男性,77%为白人/非西班牙裔,79%超重或肥胖,42%在MSD诊断指数时报告无疼痛。总体而言,BMI与疼痛之间呈J形关系(最低点 = 27 kg/m²),重度肥胖者(BMI≥40 kg/m²)最有可能报告任何疼痛(与正常体重相比的优势比 = 1.23,95%置信区间 = 1.21 - 1.26)。BMI与疼痛之间的关联因MSD而异,在骨关节炎组中关系更强,而在背部和下背部疼痛组中关系不太明显。
患有MSD的退伍军人中超重/肥胖的患病率很高。高BMI水平(>27 kg/m²)与疼痛几率增加相关,在患有骨关节炎的退伍军人中最为明显。