Chen Yong-Hsin, Lin Jia-June, Tang Hsiu-Mei, Yang Ching-Wen, Jong Gwo-Ping, Yang Yi-Sun
Department of Health Policy and Management, Chung Shan Medical University, Taichung 402, Taiwan.
Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan.
J Pers Med. 2025 Mar 23;15(4):122. doi: 10.3390/jpm15040122.
: In 2021, 10.5% of people aged 20-79 had diabetes, projected to rise to 12.2% by 2045, causing early deaths and straining healthcare systems. Musculoskeletal (MS) pain is common, affecting many workers and the general population. Prediabetes, notably impaired fasting glucose (IFG), is linked to increased MS pain risk. Objective: This study aims to assess IFG's impact on MS pain and specific pain sites to aid prevention strategies. : This cross-sectional study used the '2023 Employee Occupational Safety and Health Management Database' from a Taichung hospital. It included health checks, demographics, living and work data, and MS pain surveys. Out of 2369 staff members contacted, 1039 valid responses were analyzed, excluding incomplete data, diabetes history, or fasting blood glucose levels above 125 mg/dL. Data on sex, age, marital status, coffee and alcohol consumption, sleep duration, exercise habits, height, weight, chronic diseases, profession, work hours, shift work, and education level were collected. Fasting blood glucose was verified using American Diabetes Association criteria (100-125 mg/dL). The Nordic Musculoskeletal Questionnaire (NMQ) measured MS pain frequency and severity, creating a pain degree index. : Overall, 21.17% had IFG. Participants were mostly female (85.18%), averaging 37.50 years. Neck and shoulder pain risk was linked to sex, coffee and alcohol consumption, sleep, exercise, chronic diseases, work hours, and IFG. Ankle pain risk was linked to coffee and alcohol consumption. IFG, coffee, alcohol, sleep under 6 h, chronic diseases, and work hours were independent risk factors for neck and shoulder pain. IFG was a risk factor for those without overweight or obesity. A mediation model tested IFG's indirect effect on neck and shoulder pain among overweight or obese individuals, showing that IFG mediates the relationship between being overweight or obese and increased neck and shoulder pain risk. : Among female-dominated healthcare workers, IFG, daily coffee, recent alcohol consumption, less than 6 h of sleep, chronic diseases (excluding diabetes), and longer work hours are independent risk factors for neck and shoulder pain. IFG mainly affects these areas, increasing pain risk regardless of body weight. Healthy blood glucose levels are associated with a lack of musculoskeletal pain, suggesting a novel prevention approach needing further study.
2021年，20至79岁人群中有10.5%患有糖尿病，预计到2045年将升至12.2%，这会导致过早死亡并给医疗系统带来压力。肌肉骨骼疼痛很常见，影响着许多劳动者和普通人群。糖尿病前期，尤其是空腹血糖受损（IFG），与肌肉骨骼疼痛风险增加有关。目的：本研究旨在评估IFG对肌肉骨骼疼痛及特定疼痛部位的影响，以辅助预防策略。 这项横断面研究使用了台中一家医院的“2023年员工职业安全与健康管理数据库”。研究内容包括健康检查、人口统计学信息、生活和工作数据以及肌肉骨骼疼痛调查。在联系的2369名工作人员中，分析了1039份有效回复，排除了数据不完整、有糖尿病史或空腹血糖水平高于125mg/dL的情况。收集了有关性别、年龄、婚姻状况、咖啡和酒精摄入量、睡眠时间、运动习惯、身高、体重、慢性病、职业、工作时长、轮班工作和教育水平的数据。空腹血糖根据美国糖尿病协会标准（100 - 125mg/dL）进行核实。采用北欧肌肉骨骼问卷（NMQ）来测量肌肉骨骼疼痛的频率和严重程度，并创建疼痛程度指数。 总体而言，21.17%的人有IFG。参与者大多为女性（85.18%），平均年龄37.50岁。颈部和肩部疼痛风险与性别、咖啡和酒精摄入量、睡眠、运动、慢性病、工作时长以及IFG有关。脚踝疼痛风险与咖啡和酒精摄入量有关。IFG、咖啡、酒精、睡眠不足6小时、慢性病和工作时长是颈部和肩部疼痛的独立危险因素。IFG是体重正常者的危险因素。一个中介模型测试了IFG在超重或肥胖个体中对颈部和肩部疼痛的间接影响，结果表明IFG介导了超重或肥胖与颈部和肩部疼痛风险增加之间的关系。 在以女性为主的医护人员中，IFG、每日咖啡摄入量、近期饮酒、睡眠不足6小时、慢性病（不包括糖尿病）和工作时长较长是颈部和肩部疼痛的独立危险因素。IFG主要影响这些部位，无论体重如何都会增加疼痛风险。血糖水平正常与无肌肉骨骼疼痛相关，这表明需要进一步研究一种新的预防方法。
