Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Circ Arrhythm Electrophysiol. 2020 Apr;13(4):e008239. doi: 10.1161/CIRCEP.119.008239. Epub 2020 Mar 18.
Left bundle branch block may be due to conduction system degeneration or a reflection of myocardial pathology. Left bundle branch block may also develop following aortic valve disease or cardiac procedures. Patients with heart failure with reduced ejection fraction and left bundle branch block may respond positively to cardiac resynchronization therapy. Lead placement via the coronary sinus is the mainstay approach of cardiac resynchronization therapy. However, other options, including physiological pacing, are being explored. In this review, we summarize the salient pathophysiologic and clinical aspects of left bundle branch block, as well as current and future strategies for management.
左束支传导阻滞可能是由于传导系统退化或心肌病理的反映。左束支传导阻滞也可能在主动脉瓣疾病或心脏手术后发展。射血分数降低的心力衰竭伴左束支传导阻滞的患者可能对心脏再同步治疗有积极反应。通过冠状窦放置导联是心脏再同步治疗的主要方法。然而，其他选择，包括生理性起搏，正在被探索。在这篇综述中，我们总结了左束支传导阻滞的显著病理生理和临床方面，以及当前和未来的管理策略。
