Tang B W, Wang X M, Wu J
School of Public Health, Inner Mongolia Medical University, Hohhot 010110, China.
National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Diseases Control and Prevention, Beijing 100050, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Mar 6;54(3):327-331. doi: 10.3760/cma.j.issn.0253-9624.2020.03.016.
In recent years, the high infection rate of Helicobacter pylori and its impact on cardiovascular disease have attracted public attention. It may directly affect coronary heart disease, stroke, etc. through various mechanisms such as inflammation, immune response, and damage to endothelial cells. It could also play an important role in the formation of cardiovascular disease risk factors such as atherosclerosis, hypertension, hyperhomocysteinemia, and dyslipidemia. However, domestic and international research results are still inconsistent, and a large number of experiments are still required to confirm it to take effective measures to control the incidence of cardiovascular disease. This article reviews the prevalence of Helicobacter pylori and cardiovascular disease, the interaction mechanisms and the status of relevant domestic and international researches.
近年来，幽门螺杆菌的高感染率及其对心血管疾病的影响已引起公众关注。它可能通过炎症、免疫反应和内皮细胞损伤等多种机制直接影响冠心病、中风等。它也可能在动脉粥样硬化、高血压、高同型半胱氨酸血症和血脂异常等心血管疾病危险因素的形成中发挥重要作用。然而，国内外的研究结果仍不一致，仍需要大量实验来证实，以便采取有效措施控制心血管疾病的发病率。本文综述了幽门螺杆菌与心血管疾病的流行情况、相互作用机制以及国内外相关研究现状。
