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与代谢综合征相关的参数对动脉高血压的影响。

Impact of -Related Metabolic Syndrome Parameters on Arterial Hypertension.

作者信息

Kountouras Jannis, Papaefthymiou Apostolis, Polyzos Stergios A, Deretzi Georgia, Vardaka Elisabeth, Soteriades Elpidoforos S, Tzitiridou-Chatzopoulou Maria, Gkolfakis Paraskevas, Karafyllidou Kyriaki, Doulberis Michael

机构信息

Second Medical Clinic, School of Medicine, Ippokration Hospital, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.

Department of Gastroenterology, University Hospital of Larisa, 41110 Larisa, Greece.

出版信息

Microorganisms. 2021 Nov 14;9(11):2351. doi: 10.3390/microorganisms9112351.

Abstract

Arterial hypertension is a risk factor for several pathologies, mainly including cardio-cerebrovascular diseases, which rank as leading causes of morbidity and mortality worldwide. Arterial hypertension also constitutes a fundamental component of the metabolic syndrome. infection is one of the most common types of chronic infection globally and displays a plethora of both gastric and extragastric effects. Among other entities, has been implicated in the pathogenesis of the metabolic syndrome. Within this review, we illustrate the current state-of-the-art evidence, which may link several components of the -related metabolic syndrome, including non-alcoholic fatty liver disease and arterial hypertension. In particular, current knowledge of how exerts its virulence through dietary, inflammatory and metabolic pathways will be discussed. Although there is still no causative link between these entities, the emerging evidence from both basic and clinical research supports the proposal that several components of the infection-related metabolic syndrome present an important risk factor in the development of arterial hypertension. The triad of infection, the metabolic syndrome, and hypertension represents a crucial worldwide health problem on a pandemic scale with high morbidity and mortality, like COVID-19, thereby requiring awareness and appropriate management on a global scale.

摘要

动脉高血压是多种疾病的危险因素,主要包括心脑血管疾病,而心脑血管疾病是全球发病和死亡的主要原因。动脉高血压也是代谢综合征的一个基本组成部分。[某种感染]是全球最常见的慢性感染类型之一,具有大量的胃部和胃外影响。在其他疾病中,[某种感染]与代谢综合征的发病机制有关。在本综述中,我们阐述了当前的最新证据,这些证据可能将与[某种感染]相关的代谢综合征的几个组成部分联系起来,包括非酒精性脂肪性肝病和动脉高血压。特别是,将讨论目前关于[某种感染]如何通过饮食、炎症和代谢途径发挥其毒力的知识。尽管这些疾病之间仍没有因果联系,但基础研究和临床研究中出现的证据支持这样的观点,即与[某种感染]相关的代谢综合征的几个组成部分是动脉高血压发展的重要危险因素。[某种感染]、代谢综合征和高血压这三者构成了一个在全球范围内至关重要的健康问题,其发病率和死亡率都很高,就像COVID - 19一样,因此需要在全球范围内提高认识并进行适当管理。 (注:原文中“Among other entities, has been implicated in the pathogenesis of the metabolic syndrome.”以及多处未明确的“”部分内容缺失或不完整,翻译时按原文呈现)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca1/8618184/504aed6c00d8/microorganisms-09-02351-g001.jpg

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