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一种“哲学分子”,氢气或可攻克衰老和顽疾

A "philosophical molecule," hydrogen may overcome senescence and intractable diseases.

机构信息

MiZ Company Limited, Kamakura, Japan.

Faculty of Environment and Information Studies, Keio University, Fujisawa, Japan.

出版信息

Med Gas Res. 2020 Jan-Mar;10(1):47-49. doi: 10.4103/2045-9912.279983.

DOI:10.4103/2045-9912.279983
PMID:32189669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7871941/
Abstract

It has been revealed that the cause of senescence and diseases is associated with the reactive oxygen species "hydroxyl radicals" (·OH). Senescence and diseases may be overcome as long as we can scavenge •OH mostly produced in mitochondria. It is one and only one "molecular hydrogen" (H) that can both penetrate into the mitochondria and scavenge the •OH. The H in the body can function in disease prevention and recovery. H gas is explosive so that a safe hydrogen inhaler has to be developed for home use. We would like to advocate the great use of H.

摘要

现已发现,衰老和疾病的原因与活性氧“羟自由基”(·OH)有关。只要我们能够清除线粒体中产生的大部分·OH,就有可能克服衰老和疾病。只有一种“氢气”(H)既能穿透线粒体又能清除·OH。体内的 H 可以在疾病预防和康复中发挥作用。H 气体是易爆的,因此必须开发安全的氢气吸入器供家庭使用。我们希望提倡大量使用 H。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc82/7871941/2c20208e4324/MGR-10-47-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc82/7871941/2c20208e4324/MGR-10-47-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc82/7871941/2c20208e4324/MGR-10-47-g001.jpg

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Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy.多前药纳米反应器诱导的线粒体特异性药物释放和活性氧爆发可以增强化疗。
Nat Commun. 2019 Apr 12;10(1):1704. doi: 10.1038/s41467-019-09566-3.
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Hydrogen Flush After Cold Storage as a New End-Ischemic Ex Vivo Treatment for Liver Grafts Against Ischemia/Reperfusion Injury.
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Antioxidants (Basel). 2023 Nov 30;12(12):2062. doi: 10.3390/antiox12122062.
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Successful treatment of myalgic encephalomyelitis/chronic fatigue syndrome using hydrogen gas: four case reports.氢气成功治疗肌痛性脑脊髓炎/慢性疲劳综合征:四例病例报告
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