潜在的麻醉气体对神经胶质瘤的作用规则。
Potential rules of anesthetic gases on glioma.
机构信息
Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
出版信息
Med Gas Res. 2020 Jan-Mar;10(1):50-53. doi: 10.4103/2045-9912.279984.
Abstract
Glioma is one of the most frequent primary brain tumors. Currently, the most common therapeutic strategy for patients with glioma is surgical resection combined with radiotherapy or/and adjuvant chemotherapy. However, due to the metastatic and invasive nature of glioma cells, the recurrence rate is high, resulting in poor prognosis. In recent years, gas therapy has become an emerging treatment. Studies have shown that the proliferation, metastasis and invasiveness of glioma cells exposed to anesthetic gases are obviously inhibited. Therefore, anesthetic gas may play a special therapeutic role in gliomas. In this review, we aim to collect existing research and summarize the rules of using anesthetic gases on glioma, providing potential strategies for further clinical treatment.
摘要
脑胶质瘤是最常见的原发性脑肿瘤之一。目前，脑胶质瘤患者最常见的治疗策略是手术切除联合放疗或/和辅助化疗。然而，由于脑胶质瘤细胞具有转移性和侵袭性，复发率较高，预后较差。近年来，气体治疗已成为一种新兴的治疗方法。研究表明，暴露于麻醉气体的脑胶质瘤细胞的增殖、转移和侵袭明显受到抑制。因此，麻醉气体可能在脑胶质瘤中发挥特殊的治疗作用。在这篇综述中，我们旨在收集现有的研究并总结麻醉气体对脑胶质瘤的作用规律，为进一步的临床治疗提供潜在策略。
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