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慢性特发性中性粒细胞减少症:一位牙周病医生的诊断。

Chronic idiopathic neutropenia: A periodontist's diagnosis.

作者信息

Raj Subash Chandra, Mahapatra Annuroopa, Agrawal Poonam, Patnaik Kaushik, Pradhan Shib Shankar

机构信息

Department of Periodontics, SCB Dental College and Hospital, Cuttack, Odisha, India.

出版信息

J Indian Soc Periodontol. 2020 Mar-Apr;24(2):173-177. doi: 10.4103/jisp.jisp_149_19. Epub 2020 Jan 27.

Abstract

Our aim is to report the periodontal findings of a 10-year-old boy who visited the outpatient department of periodontology, with the chief complaint of swelling in the right cheek region for the last 2 months, increasing mobility of the teeth, and frequent bleeding from the gums. Since the age of 4 years, he suffered from recurrent febrile episodes, with boils and furuncles on the face. After several hematological and immunological investigations, he was diagnosed with chronic idiopathic neutropenia. He was prescribed a 150 μg subcutaneous injection of recombinant granulocyte colony-stimulating factor, once daily for 8 days. For reducing oral inflammation, he was advised an oral rinse of 15 ml of chlorhexidine gluconate (0.12%) twice daily and advised for a routine periodontal checkup, every 3-4 weeks for evaluation, maintenance, and avoiding any acute inflammatory flare-ups.

摘要

我们的目的是报告一名10岁男孩的牙周检查结果。该男孩前往牙周病门诊就诊,主要症状为右脸颊区域肿胀2个月、牙齿松动加剧以及牙龈频繁出血。自4岁起,他反复出现发热症状,面部有疖肿。经过多项血液学和免疫学检查,他被诊断为慢性特发性中性粒细胞减少症。给他开了每日一次、共8天的150μg皮下注射重组粒细胞集落刺激因子的处方。为减轻口腔炎症,建议他每天两次用15ml葡萄糖酸氯己定(0.12%)进行口腔冲洗,并建议每3 - 4周进行一次常规牙周检查,以进行评估、维护并避免任何急性炎症发作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f55a/7069110/4d06398ef5ca/JISP-24-173-g001.jpg

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