Kuberappa Puneeth H, Anuradha Ananthaneni, Kiresur Mohammad Asif, Bagalad Bhavana S
Department of Oral Pathology and Microbiology, Saint Joseph Dental College, Eluru, Andhra Pradesh, India.
J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S2-S6. doi: 10.4103/jomfp.JOMFP_42_17. Epub 2020 Feb 28.
Ameloblastoma is the most common odontogenic tumor which presents with a variety of histopathological patterns. Among all, papilliferous keratoameloblastoma (PKA) is a very rare type which is characterized by multiple epithelial cysts of varying size, which are lined by non-keratinized papilliferous epithelium which is filled with necrotic desquamated epithelial cells. In this study, we reported PKA with characteristic ameloblastic features in a 65-year-old male patient who presented with a swelling in the right mandibular body region. This is the seventh case of PKA to be reported in the English literature till date. Present case showed multicystic areas in incision biopsy which lead to misdiagnosis as calcifying odontogenic cyst with adenomatoid odontogenic tumor, but in excision biopsy which turned out to be papilliferous keratoameloblastoma, further in this paper we had discussed all the areas which lead to misdiagnosis of calcifying odontogenic cyst with adenomatoid odontogenic tumor. In outlook, more cases will put an insight to the behavioral aspects of this rare histological type of ameloblastoma.
成釉细胞瘤是最常见的牙源性肿瘤，具有多种组织病理学模式。其中，乳头状角化成釉细胞瘤（PKA）是一种非常罕见的类型，其特征是大小不一的多个上皮囊肿，内衬非角化乳头状上皮，充满坏死脱落的上皮细胞。在本研究中，我们报告了一名65岁男性患者的PKA，其具有典型的成釉细胞特征，该患者右下颌体区域出现肿胀。这是迄今为止英文文献中报道的第七例PKA病例。目前病例在切开活检中显示多囊区域，导致误诊为伴有腺样牙源性肿瘤的钙化牙源性囊肿，但在切除活检中发现是乳头状角化成釉细胞瘤，在本文中我们进一步讨论了导致误诊为伴有腺样牙源性肿瘤的钙化牙源性囊肿的所有方面。展望未来，更多病例将有助于深入了解这种罕见组织学类型的成釉细胞瘤的行为特征。
