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上唇多形性腺瘤中的筛状结构、鳞状化生及透明细胞杂谈：一个诊断难题。

A miscellany of cribriform pattern, squamous metaplasia and clear cells in pleomorphic adenoma of upper lip: A diagnostic paradox.

作者信息

Shome Sayani, Shah Neha, Mahmud S K Abdul, Pal Mousumi

机构信息

Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Kolkata, West Bengal, India.

出版信息

J Oral Maxillofac Pathol. 2020 Feb;24(Suppl 1):S46-S50. doi: 10.4103/jomfp.JOMFP_354_19. Epub 2020 Feb 28.

DOI:10.4103/jomfp.JOMFP_354_19
PMID:32189904
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7069151/
Abstract

Pleomorphic Adenoma (PA), a benign neoplasm of glandular origin most commonly involves major salivary glands. It is rare in minor salivary glands such as hard palate, upper lip and buccal mucosa, frequently affecting middle aged females. PA comprises diverse histopathologic features of epithelial, myoepithelial and mesenchymal components. Aberrant histopathologic features in Pleomorhic Adenoma thus calls for judicious discrimination from alike entities which facilitates appropriate surgical management. Here we present a case report of PA in upper lip in a 25 year old female patient showing uncommon findings like clear cells, squamous metaplasia and cribriform pattern.

摘要

多形性腺瘤（PA）是一种起源于腺组织的良性肿瘤，最常累及大唾液腺。在小唾液腺如硬腭、上唇和颊黏膜中较为罕见，常发生于中年女性。PA具有上皮、肌上皮和间充质成分的多种组织病理学特征。多形性腺瘤中异常的组织病理学特征因此需要与相似病变进行审慎鉴别，这有助于进行恰当的手术治疗。在此，我们报告一例25岁女性患者上唇多形性腺瘤的病例，该病例呈现出透明细胞、鳞状化生和筛状结构等罕见表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/3c6e267ff482/JOMFP-24-46-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/75693471a348/JOMFP-24-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/ea393c4c309d/JOMFP-24-46-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/f332534a5d04/JOMFP-24-46-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/10b73493629e/JOMFP-24-46-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/fb940fe91c15/JOMFP-24-46-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/8ebc73246758/JOMFP-24-46-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/4844958c6cb2/JOMFP-24-46-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/74e7968ff5c2/JOMFP-24-46-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/6bdeb63cd717/JOMFP-24-46-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/3c6e267ff482/JOMFP-24-46-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/75693471a348/JOMFP-24-46-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/ea393c4c309d/JOMFP-24-46-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/f332534a5d04/JOMFP-24-46-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/10b73493629e/JOMFP-24-46-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/fb940fe91c15/JOMFP-24-46-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/8ebc73246758/JOMFP-24-46-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/4844958c6cb2/JOMFP-24-46-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/74e7968ff5c2/JOMFP-24-46-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/6bdeb63cd717/JOMFP-24-46-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c802/7069151/3c6e267ff482/JOMFP-24-46-g010.jpg

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本文引用的文献

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2
Keratinizing pleomorphic adenoma: An unusual case report.角化型多形性腺瘤：一例罕见病例报告。
J Oral Maxillofac Pathol. 2018 Jan;22(Suppl 1):S69-S72. doi: 10.4103/jomfp.JOMFP_200_17.
3
Pleomorphic adenoma involving minor salivary glands of upper lip: A rare phenomenon.累及上唇小唾液腺的多形性腺瘤：一种罕见现象。
J Cancer Res Ther. 2015 Oct-Dec;11(4):1025. doi: 10.4103/0973-1482.148682.
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An incidental finding of pleomorphic adenoma of the minor salivary glands in the skin area of the lower lip.在下唇皮肤区域意外发现小涎腺多形性腺瘤。
Eplasty. 2014 Oct 22;14:e39. eCollection 2014.
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