Debnath Subhas Chandra, Adhyapok A K
J Maxillofac Oral Surg. 2010 Jun;9(2):205-8. doi: 10.1007/s12663-010-0052-5. Epub 2010 Sep 22.
Pleomorphic adenoma is the benign tumor of salivary glands, which originates from the myoepithelial cells and intercalated duct cells. This tumor is more common in major salivary glands. This case report describes a rare and unusual lesion in a 55-year-old female, which was diagnosed as pleomorphic adenoma of the minor salivary glands in the upper lip. The tumor was a circumscribed, submucosal nodule, about 2.0 cm in diameter and was characterized by slow growth and rubbery consistency. Complete excision was performed and the histopathological analysis showed an epithelial salivary gland tumor with islands of plasmacytoid cells, duct like structures, in a variable stroma with chondroid, fibrous and myxoid appearance. No recurrence was observed 1 year after the surgery.
多形性腺瘤是唾液腺的良性肿瘤,起源于肌上皮细胞和闰管细胞。这种肿瘤在大唾液腺中更为常见。本病例报告描述了一名55岁女性的罕见且不寻常的病变,该病变被诊断为上唇小唾液腺的多形性腺瘤。肿瘤为边界清楚的黏膜下结节,直径约2.0厘米,其特点是生长缓慢且质地似橡胶。进行了完整切除,组织病理学分析显示为一种上皮性唾液腺肿瘤,伴有浆细胞样细胞岛、导管样结构,存在于具有软骨样、纤维样和黏液样外观的可变间质中。手术后1年未观察到复发。