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Urgent air transfers for acute respiratory infections among children from Northern Canada, 2005-2014.2005-2014 年加拿大北部儿童急性呼吸道感染的紧急空运。
PLoS One. 2022 Jul 28;17(7):e0272154. doi: 10.1371/journal.pone.0272154. eCollection 2022.
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Twenty "must-read" research articles for primary care providers in Nunavik: scoping study and development of an information tool.努纳维克初级保健提供者的20篇“必读”研究文章:范围界定研究与信息工具开发
Int J Circumpolar Health. 2019 Dec;78(1):1578638. doi: 10.1080/22423982.2019.1578638.
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Past, Present and Future Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children.儿童呼吸道合胞病毒感染预防与治疗的过去、现在及未来方法
Infect Dis Ther. 2018 Mar;7(1):87-120. doi: 10.1007/s40121-018-0188-z. Epub 2018 Feb 22.
3
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study.全球、区域和国家 2015 年因呼吸道合胞病毒导致的幼儿急性下呼吸道感染疾病负担估计:系统评价和建模研究。
Lancet. 2017 Sep 2;390(10098):946-958. doi: 10.1016/S0140-6736(17)30938-8. Epub 2017 Jul 7.
4
Assessment of the implementation fidelity of the Arctic Char Distribution Project in Nunavik, Quebec.魁北克努纳维克北极红点鲑分布项目实施保真度评估。
BMJ Glob Health. 2016 Oct 24;1(3):e000093. doi: 10.1136/bmjgh-2016-000093. eCollection 2016.
5
Systematic Review of the Safety and Efficacy of Palivizumab among Infants and Young Children with Cystic Fibrosis.帕利珠单抗在囊性纤维化婴幼儿中安全性和有效性的系统评价
Pharmacotherapy. 2017 Jun;37(6):755-769. doi: 10.1002/phar.1936. Epub 2017 May 29.
6
Inuit interpreters engaged in end-of-life care in Nunavik, Northern Quebec.因纽特口译员在魁北克北部努纳维克参与临终关怀工作。
Int J Circumpolar Health. 2017;76(1):1291868. doi: 10.1080/22423982.2017.1291868.
7
Hospital admissions for lower respiratory tract infections among infants in the Canadian Arctic: a cohort study.加拿大北极地区婴儿下呼吸道感染的住院情况:一项队列研究。
CMAJ Open. 2016 Oct 17;4(4):E615-E622. doi: 10.9778/cmajo.20150051. eCollection 2016 Oct-Dec.
8
Understanding the role of Indigenous community participation in Indigenous prenatal and infant-toddler health promotion programs in Canada: A realist review.了解加拿大原住民社区参与原住民产前和婴幼儿健康促进项目的作用:一项现实主义综述。
Soc Sci Med. 2016 Feb;150:128-43. doi: 10.1016/j.socscimed.2015.12.019. Epub 2015 Dec 18.
9
Eighteen Years of Respiratory Syncytial Virus Surveillance: Changes in Seasonality and Hospitalization Rates in Southwestern Alaska Native Children.18年呼吸道合胞病毒监测:阿拉斯加西南部原住民儿童季节性变化及住院率情况
Pediatr Infect Dis J. 2015 Sep;34(9):945-50. doi: 10.1097/INF.0000000000000772.
10
The real-life effectiveness of palivizumab for reducing hospital admissions for respiratory syncytial virus in infants residing in Nunavut.帕利珠单抗对降低努纳武特地区婴儿因呼吸道合胞病毒导致的住院率的实际效果。
Can Respir J. 2014 May-Jun;21(3):185-9. doi: 10.1155/2014/941367. Epub 2013 Dec 23.

可行性与伦理问题:魁北克努纳维克地区医护人员对一项新的呼吸道合胞病毒预防项目的经验与担忧

Feasibility and ethical issues: experiences and concerns of healthcare workers regarding a new RSV prophylaxis programme in Nunavik, Quebec.

作者信息

Lorcy Armelle, Gilca Rodica, Dubé Eve, Rochette Marie, De Serres Gaston

机构信息

Infectious and immune diseases, CHU De Québec-Université Laval Research Centre, Quebec City, Quebec, Canada.

Enseignement Et Recherche En Ethnologie Amérindienne (EREA), Centre of the LESC (CNRS, UMR 7186), Paris, France.

出版信息

Int J Circumpolar Health. 2020 Dec;79(1):1742564. doi: 10.1080/22423982.2020.1742564.

DOI:10.1080/22423982.2020.1742564
PMID:32191589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7144279/
Abstract

: The respiratory syncytial virus (RSV) is a major cause of hospitalisation in young Inuit children. Prophylaxis with palivizumab is routinely recommended for premature infants and those with severe pulmonary or cardiac diseases. In the fall 2016, the Quebec Ministry of Health expanded the criteria to include healthy full-term (HFT) newborns from Nunavik based on their high RSV hospitalisation rates.: The aim of this study was to describe the impact of this programme on Nunavik health services during the first RSV season after its implementation (2016-2017) by studying challenges, concerns and needs of healthcare workers (HCWs).: An ethnographic approach was used. Semi-structured interviews focusing on HCWs experiences, and opinions to improve the new programme were conducted with 20 HCWs involved in its implementation.: Main reported challenges and concerns were: additional work(over)load, lack of information and evidence about the need and efficacy of palivizumab in HFT newborns, communication issues between stakeholders, and ethical issues regarding the Inuit population.: The study revealed significant feasibility and acceptability issues. The programme was highly resource consuming. To address HCWs' concerns, evidence-based data regarding palivizumab effectiveness in HFT infants, as well as consultation and involvement of Inuit population are warranted.

摘要

呼吸道合胞病毒(RSV)是因纽特幼儿住院的主要原因。对于早产儿以及患有严重肺部或心脏疾病的患儿,常规推荐使用帕利珠单抗进行预防。2016年秋季,魁北克省卫生部扩大了标准,将努纳维克地区健康的足月儿纳入其中,因为他们的RSV住院率很高。本研究的目的是通过研究医护人员面临的挑战、担忧和需求,描述该项目在实施后的首个RSV季节(2016 - 2017年)对努纳维克地区医疗服务的影响。采用了人种志研究方法。对参与该项目实施的20名医护人员进行了半结构化访谈,重点了解他们的经历以及对改进新项目的意见。主要报告的挑战和担忧包括:额外的工作负担、缺乏关于帕利珠单抗在足月儿中的必要性和有效性的信息及证据、利益相关者之间的沟通问题以及与因纽特人群相关的伦理问题。该研究揭示了显著的可行性和可接受性问题。该项目资源消耗巨大。为解决医护人员的担忧,有必要提供关于帕利珠单抗在足月儿中有效性的循证数据,以及因纽特人群的咨询和参与。