甘露糖、ElliroseTM 和植物乳杆菌治疗尿路感染（rUTIs）复发的效果：泌尿科医生对其临床应用的认知调查。

Effects of D-Mannose, ElliroseTM and Lactobacillus Plantarum in treatment of urinary tract recurrent infections (rUTIs): A survey of urologists knowledge about its clinical application.

机构信息

Department of Urology, University of Modena and Reggio Emilia, Modena, Italy.

U.O.C. of Urology, University-Hospital of Parma, Parma, Italy.

出版信息

Acta Biomed. 2020 Mar 19;91(1):15-20. doi: 10.23750/abm.v91i1.8607.

DOI:10.23750/abm.v91i1.8607

PMID:32191649

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7569579/

Abstract

BACKGROUND AND AIM OF THE WORK

Urinary tract infections (UTIs) and recurrent urinary tract infections (rUTIs) are widespread disease and almost half of all women will experience at least one episode of cystitis during their life. Aim of this study was to review the evidence of literature about the therapeutic and preventive effects of a product containing D-Mannose, ElliroseTM and Lactobacollus Plantarum on patients' symptoms, quality of life and recurrence of UTIs and to investigate the practicing urologists' knowledge about the clinical application of this product.

MATERIALS

We administrated an investigational survey about clinical use of a phytotherapeutic product made of D-Mannose, ElliroseTM and Lactobacollus Plantarum to 12 residents in Urology at the University of Modena and Reggio Emilia and to 32 urologists working in the provinces of Modena, Reggio Emilia and Parma.

RESULTS

61% of physicians have diagnosed rUTIs in 3-6 patients during a month, and 7% of them in more than 6 patients during the same period of time. By these results rUTIs appear as common pathological conditions. 59% prescribed the product at least 1 time a month and 14% prescribed it more than 5 times. 43% administrated the product after out-patient invasive examinations as cistoscopy and urodynamic exam for UTIs prevention. 55% noticed a significant improvement in patient's QoL (Quality of Life) suffering from rUTIs. Furthermore 48% also reported a significant effect for the improvement of urinary symptoms of patients. No gastric or general side effects have been noticed during the administration period. Finally the cost of integrator has been reported affordable for the great majority of patients.

CONCLUSIONS

Many studies in Literature have shown that D-Mannose and H. sabdariffa (ElliroseTM) reduce the risk of development of rUTIs opposing colonization and proliferation of uropathogenic bacteria in urinary tract. Our investigational survey about the administration of a phytotherapeutic product showed that this product is well-known and has a proved positive impact.

摘要

背景与目的

尿路感染（UTI）和复发性尿路感染（rUTI）是广泛存在的疾病，几乎一半的女性在其一生中都会经历至少一次膀胱炎。本研究旨在回顾有关 D-甘露糖、ElliroseTM 和植物乳杆菌治疗和预防作用的文献证据，以评估该产品对患者症状、生活质量和 UTI 复发的影响，并调查泌尿科医生对该产品临床应用的了解。

材料

我们向摩德纳和雷焦艾米利亚大学的 12 名泌尿科住院医师以及在摩德纳、雷焦艾米利亚和帕尔马省工作的 32 名泌尿科医生发放了关于 D-甘露糖、ElliroseTM 和植物乳杆菌植物疗法产品临床应用的调查。

结果

61%的医生在一个月内诊断出 3-6 例 rUTI，7%的医生在同一时期诊断出超过 6 例 rUTI。由此可见，rUTI 是一种常见的病理情况。59%的医生每月至少开一次该产品，14%的医生每月开超过 5 次。43%的医生在门诊侵入性检查（如膀胱镜检查和尿动力学检查）后为预防 UTI 而开具该产品。55%的医生注意到 rUTI 患者的生活质量（QoL）显著改善。此外，48%的医生还报告说，该产品对改善患者的尿路症状也有显著效果。在治疗期间，未发现胃部或全身副作用。最后，该整合剂的费用被报告为大多数患者负担得起。