Milandri Riccardo, Maltagliati Matteo, Bocchialini Tommaso, Del Prete Chiara, Bianchi Giampaolo, Rocco Bernardo M, Micali Salvatore
Department of Urology, University of Modena and Reggio Emilia, Modena, Italy.
Urologia. 2019 Aug;86(3):122-125. doi: 10.1177/0391560318798291. Epub 2018 Sep 12.
The urodynamic study is an invasive examination that allows a thorough evaluation of the functional activity of the lower urinary tract (bladder, urethra). The execution of urodynamic study exposes the patient to the risk of contracting infections of the lower urinary tract. Prevention of urinary tract infections consists in the avoidance of risk factors and prophylaxis with antimicrobial and non-antimicrobial measures. In this article, we aimed to evaluate the effectiveness of a phytotherapeutic product composed of D-mannose, , and in the prevention of infectious events following invasive urodynamic examination.
We selected 100 female consecutive patients (age 19-87 years) that underwent urodynamic invasive procedure. We prescribed 14-day therapy with D-mannose, , and to these 100 patients after urodynamic invasive test. After that, we have examined urine cultures and urinary symptoms through telephone interviews and hospital outpatient visits to evaluate the possible presence of urinary tract infections.
Urinary tract infections were observed through urine culture in 13% of the selected patients; of the 13 urinary tract infections, 9 were observed in patients with urinary tract recurrent infections in the last year and the other 4 cases were associated with patients with no urinary infection in the last year. Three women reported some urinary symptoms and underwent antibiotic therapy. The other 10 cases were classified as asymptomatic bacteriuria. Three cases were related to patients presenting with pelvic organ prolapse. Eight cases were instead related to significant post-voiding residue (>100). Six patients with urinary tract infection reported constipation in the last year. All patients completed the prescribed therapy due to the affordable price of the product and no side effects have been reported.
Our study about the administration of D-mannose, , and after invasive urodynamic examination underlined how this phytotherapeutic product can reduce the risk of bacteriuria and urinary tract infection in women.
尿动力学研究是一种侵入性检查，可对下尿路（膀胱、尿道）的功能活动进行全面评估。进行尿动力学研究使患者面临下尿路感染的风险。预防尿路感染包括避免危险因素以及采用抗菌和非抗菌措施进行预防。在本文中，我们旨在评估一种由D - 甘露糖等组成的植物治疗产品在预防侵入性尿动力学检查后感染事件方面的有效性。
我们选取了100例连续的女性患者（年龄19 - 87岁），她们接受了尿动力学侵入性检查。在尿动力学侵入性检查后，我们给这100例患者开了为期14天的D - 甘露糖等治疗方案。之后，我们通过电话访谈和医院门诊就诊检查尿培养和尿路症状，以评估是否可能存在尿路感染。
通过尿培养在13%的所选患者中观察到尿路感染；在这13例尿路感染中，9例发生在去年有尿路反复感染的患者中，另外4例与去年无尿路感染的患者相关。3名女性报告了一些尿路症状并接受了抗生素治疗。其他10例被归类为无症状菌尿。3例与盆腔器官脱垂患者有关。另外8例与排尿后残余尿量显著（>100）有关。6例尿路感染患者报告去年有便秘。由于该产品价格实惠，所有患者都完成了规定的治疗，且未报告有副作用。
我们关于侵入性尿动力学检查后给予D - 甘露糖等的研究强调了这种植物治疗产品如何能够降低女性菌尿和尿路感染的风险。
