Carpenter P M, Atai M, Hoit B
Department of Pathology, UCSD Medical Center.
Am J Cardiovasc Pathol. 1988;2(3):273-6.
We report a case of mitral valve aneurysm and severe mitral regurgitation complicating infective endocarditis in a patient with hypertrophic cardiomyopathy. 2-dimensional echocardiography revealed a saccular structure in the anterior mitral leaflet that bulged into the left atrium throughout the cardiac cycle. Pathology of the excised valve showed inflammation, early repair and perforation of the aneurysm. Concurrent mitral insufficiency or trauma resulting from septal-anterior mitral leaflet contact may predispose to valvular infection. The repair process of this damaged focus and the loss of the elastic properties of the valve may contribute to aneurysm formation. The aneurysm in this case formed in less than 5 weeks.
我们报告了一例肥厚型心肌病患者并发感染性心内膜炎伴二尖瓣动脉瘤及严重二尖瓣反流的病例。二维超声心动图显示二尖瓣前叶有一个囊状结构，在整个心动周期中均凸向左心房。切除瓣膜的病理检查显示有炎症、动脉瘤早期修复及穿孔。二尖瓣前叶与室间隔接触导致的并发二尖瓣关闭不全或创伤可能易引发瓣膜感染。该受损病灶的修复过程及瓣膜弹性特性的丧失可能促使动脉瘤形成。本例中的动脉瘤在不到5周内形成。
