一种源自人肺腺癌组织的糖肽。

A glycopeptide from adenocarcinoma tissue of human lung.

作者信息

Masuda H, Ozeki T

机构信息

Third Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Fukuoka, Japan.

出版信息

Biochem Med Metab Biol. 1988 Aug;40(1):1-7. doi: 10.1016/0885-4505(88)90098-9.

DOI:10.1016/0885-4505(88)90098-9

PMID:3219227

Abstract

A glycopeptide from adenocarcinoma tissue of human lung was extracted by protein digestion with papain (EC 3.4.22.2) and trypsin (EC 3.4.21.4). This component was isolated by Pevikon block electrophoresis. It possessed hexose, glucosamine, fucose, galactosamine, and sialic acid. In its carbohydrate composition and also the abundance of threonin in the peptide moiety it was quite similar to the glycoprotein from gastrointestinal tract. The physical characteristic of the two, such as their optical rotation and viscosity, were also very similar each other.

摘要

用木瓜蛋白酶（EC 3.4.22.2）和胰蛋白酶（EC 3.4.21.4）消化蛋白质，从人肺腺癌组织中提取出一种糖肽。该成分通过聚乙烯醇缩甲醛块状电泳进行分离。它含有己糖、氨基葡萄糖、岩藻糖、半乳糖胺和唾液酸。在其碳水化合物组成以及肽部分中苏氨酸的含量方面，它与来自胃肠道的糖蛋白非常相似。两者的物理特性，如旋光性和粘度，也彼此非常相似。