Toll-like receptor 9, a possible blocker of non-alcoholic steatohepatitis?
作者信息
Jeong Soung Won
机构信息
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
出版信息
Clin Mol Hepatol. 2020 Apr;26(2):185-186. doi: 10.3350/cmh.2020.0046. Epub 2020 Mar 23.
Abstract
摘要
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本文引用的文献
1
Limited expression of TLR9 on T cells and its functional consequences in patients with nonalcoholic fatty liver disease.非酒精性脂肪性肝病患者T细胞上TLR9的表达受限及其功能后果
Clin Mol Hepatol. 2020 Apr;26(2):216-226. doi: 10.3350/cmh.2019.0074. Epub 2019 Dec 5.
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Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis.非酒精性脂肪性肝病与糖尿病。第一部分：流行病学和诊断。
Diabetes Metab J. 2019 Feb;43(1):31-45. doi: 10.4093/dmj.2019.0011.
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Recent research trends and updates on nonalcoholic fatty liver disease.非酒精性脂肪性肝病的最新研究趋势和进展。
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Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9.肝细胞线粒体DNA通过激活TLR9驱动非酒精性脂肪性肝炎。
J Clin Invest. 2016 Mar 1;126(3):859-64. doi: 10.1172/JCI83885. Epub 2016 Jan 25.
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M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease.M2 库普弗细胞促进 M1 库普弗细胞凋亡：一种针对酒精性和非酒精性脂肪性肝病的保护机制。
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Macrophage plasticity and polarization: in vivo veritas.巨噬细胞的可塑性和极化：体内的真实情况。
J Clin Invest. 2012 Mar;122(3):787-95. doi: 10.1172/JCI59643. Epub 2012 Mar 1.
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Protective and pathogenic functions of macrophage subsets.巨噬细胞亚群的保护和致病功能。
Nat Rev Immunol. 2011 Oct 14;11(11):723-37. doi: 10.1038/nri3073.
8
Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice.Toll 样受体 9 通过诱导小鼠白细胞介素-1β促进脂肪性肝炎。
Gastroenterology. 2010 Jul;139(1):323-34.e7. doi: 10.1053/j.gastro.2010.03.052. Epub 2010 Mar 27.
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Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.人类Toll样受体9通过物种特异性的CpG基序识别赋予对细菌DNA的反应性。
Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9237-42. doi: 10.1073/pnas.161293498. Epub 2001 Jul 24.
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A Toll-like receptor recognizes bacterial DNA.一种Toll样受体可识别细菌DNA。
Nature. 2000 Dec 7;408(6813):740-5. doi: 10.1038/35047123.
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