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Myelodysplastic syndrome patient-derived xenografts: from no options to many.

作者信息

Côme Christophe, Balhuizen Alexander, Bonnet Dominique, Porse Bo T

机构信息

The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark.

Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, Denmark.

出版信息

Haematologica. 2020 Apr;105(4):864-869. doi: 10.3324/haematol.2019.233320. Epub 2020 Mar 19.

DOI:10.3324/haematol.2019.233320
PMID:32193253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7109759/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4e/7109759/131031127753/105864.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4e/7109759/131031127753/105864.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf4e/7109759/131031127753/105864.fig1.jpg

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A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.
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Development of iPSC-derived human bone marrow organoid for autonomous hematopoiesis and patient-derived HSPC engraftment.用于自主造血和患者来源造血干细胞移植的诱导多能干细胞衍生的人骨髓类器官的开发。
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