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脓毒症性心肌病的现状:基础科学与临床进展

Current Status of Septic Cardiomyopathy: Basic Science and Clinical Progress.

作者信息

Lin Huan, Wang Wenting, Lee Madeline, Meng Qinghe, Ren Hongsheng

机构信息

Department of Intensive Care Unit, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

Dartmouth College, Hanover, NH, United States.

出版信息

Front Pharmacol. 2020 Mar 3;11:210. doi: 10.3389/fphar.2020.00210. eCollection 2020.

DOI:10.3389/fphar.2020.00210
PMID:32194424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7062914/
Abstract

Septic cardiomyopathy (SCM) is a complication that is sepsis-associated cardiovascular failure. In the last few decades, there is progress in diagnosis and treatment despite the lack of consistent diagnostic criteria. According to current studies, several hypotheses about pathogenic mechanisms have been revealed to elucidate the pathophysiological characteristics of SCM. The objective of this manuscript is to review literature from the past 5 years to provide an overview of current knowledge on pathogenesis, diagnosis and treatment in SCM.

摘要

脓毒症性心肌病(SCM)是一种与脓毒症相关的心血管功能衰竭并发症。在过去几十年中,尽管缺乏一致的诊断标准,但在诊断和治疗方面仍取得了进展。根据目前的研究,已经揭示了几种关于致病机制的假说,以阐明SCM的病理生理特征。本手稿的目的是回顾过去5年的文献,以概述目前关于SCM发病机制、诊断和治疗的知识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36a8/7062914/686262f3695f/fphar-11-00210-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36a8/7062914/3910825b0c64/fphar-11-00210-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36a8/7062914/686262f3695f/fphar-11-00210-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36a8/7062914/3910825b0c64/fphar-11-00210-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36a8/7062914/686262f3695f/fphar-11-00210-g002.jpg

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Clin Immunol. 2020 Jan;210:108264. doi: 10.1016/j.clim.2019.108264. Epub 2019 Oct 23.
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