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支持基础化学毒理学研究以指导医学对策开发：美国国立卫生研究院化学对策研究计划。

Supporting Fundamental Chemical Toxicology Research To Inform Medical Countermeasure Developments: The National Institutes of Health Chemical Countermeasures Research Program.

作者信息

Yeung David T, Harper Jill R, Platoff Gennady E

机构信息

Department of Health and Human Services, National Institute of Allergy and Infectious Diseases/National Institutes of Health (NIAID/NIH), Bethesda, Maryland 20892, United States.

出版信息

Chem Res Toxicol. 2020 Apr 20;33(4):855-859. doi: 10.1021/acs.chemrestox.0c00086. Epub 2020 Mar 20.

DOI:10.1021/acs.chemrestox.0c00086
PMID:32196324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7174080/
Abstract

A high-consequence chemical emergency is a major public health concern. In the United States, the National Institute of Allergy and Infectious Diseases within the National Institutes of Health pioneers discovery and early development of critical medical countermeasures against chemical threats.

摘要

高后果化学紧急情况是一个重大的公共卫生问题。在美国，国立卫生研究院下属的国家过敏和传染病研究所率先开展针对化学威胁的关键医学应对措施的发现和早期研发工作。

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本文引用的文献

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Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures.正电子发射断层扫描研究有机磷化学威胁和肟类解毒剂对策。
Neurobiol Dis. 2020 Jan;133:104455. doi: 10.1016/j.nbd.2019.04.011. Epub 2019 Apr 22.
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Airway tissue plasminogen activator prevents acute mortality due to lethal sulfur mustard inhalation.气道组织纤溶酶原激活剂可预防因吸入致死性硫芥导致的急性死亡。
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HHS Releases New Strategy for Emergency Medical Countermeasures Enterprise.美国卫生与公众服务部发布紧急医疗对策企业新战略。
Biosecur Bioterror. 2012 Sep;10(3):247-54. doi: 10.1089/bsp.2012.0816.
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Airway obstruction due to bronchial vascular injury after sulfur mustard analog inhalation.吸入芥子气类似物后支气管血管损伤导致的气道阻塞。
Am J Respir Crit Care Med. 2010 Dec 1;182(11):1352-61. doi: 10.1164/rccm.200910-1618OC. Epub 2010 Jul 16.
5
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