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Pathophysiology of diseases involving intestinal brush-border proteins.

作者信息

Alpers D H, Seetharam B

出版信息

N Engl J Med. 1977 May 5;296(18):1047-50. doi: 10.1056/NEJM197705052961808.

DOI:10.1056/NEJM197705052961808
PMID:321966
Abstract
摘要

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Pathophysiology of diseases involving intestinal brush-border proteins.涉及肠道刷状缘蛋白疾病的病理生理学
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2
Disaccharidase activities of duodenal mucosa in children. (Normal subjects, coeliac DISEASE, malnutrition, cystic fibrosis of pancreas, other chronic enteropathies).儿童十二指肠黏膜双糖酶活性。（正常受试者、乳糜泻、营养不良、胰腺囊性纤维化、其他慢性肠病）
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A digestive-absorptive surface as illustrated by the intestinal cell brush border.如肠细胞刷状缘所示的消化吸收表面。
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Orthotopic transplantation of intestinal mucosal organoids in rodents.啮齿动物肠道黏膜类器官的原位移植。
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Pathogenesis of mucosal injury in the blind loop syndrome. Brush border enzyme activity and glycoprotein degradation.盲袢综合征黏膜损伤的发病机制。刷状缘酶活性与糖蛋白降解。
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On the cellular distribution of sucrase and enterokinase in different populations of rat intestinal epithelial cells isolated by a vibration method.关于用振动法分离的大鼠肠上皮细胞不同群体中蔗糖酶和肠激酶的细胞分布
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A unique subset of rat and human intestinal villus cells express the cystic fibrosis transmembrane conductance regulator.大鼠和人类肠道绒毛细胞中的一个独特亚群表达囊性纤维化跨膜传导调节因子。
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The responses of rat intestinal brush border and cytosol peptide hydrolase activities to variation in dietary protein content: dietary regulation of intestinal peptide hydrolases.大鼠肠道刷状缘和胞质溶胶肽水解酶活性对膳食蛋白质含量变化的反应：肠道肽水解酶的膳食调节
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Phosphorylation of specific rat intestinal microvillus and basal-lateral membrane proteins by cyclic nucleotides.
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Circadian rhythm of intestinal sucrase activity in rats. Mechanism of enzyme change.大鼠肠道蔗糖酶活性的昼夜节律。酶变化的机制。
J Clin Invest. 1980 May;65(5):1174-81. doi: 10.1172/JCI109772.
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Microvillous surface area in secondary disaccharidase deficiency.继发性双糖酶缺乏症中的微绒毛表面积
Gut. 1980 Jan;21(1):44-8. doi: 10.1136/gut.21.1.44.
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Arch Dermatol Res. 1982;273(1-2):85-90. doi: 10.1007/BF00509030.
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Infect Immun. 1980 Jun;28(3):1019-27. doi: 10.1128/iai.28.3.1019-1027.1980.
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Diamine oxidase (histaminase). A circulating marker for rat intestinal mucosal maturation and integrity.二胺氧化酶（组胺酶）。大鼠肠黏膜成熟和完整性的循环标志物。
J Clin Invest. 1980 Jul;66(1):66-70. doi: 10.1172/JCI109836.
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A freeze-fracture study of perinatal changes of intramembranous particles in microvilli of absorptive cells in mouse small intestine.小鼠小肠吸收细胞微绒毛膜内颗粒围产期变化的冰冻断裂研究。
Cell Tissue Res. 1983;233(3):549-61. doi: 10.1007/BF00212224.
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Immunocytochemical localization of the intrinsic factor-cobalamin receptor in dog-ileum: distribution of intracellular receptor during cell maturation.犬回肠中内因子 - 钴胺素受体的免疫细胞化学定位：细胞成熟过程中细胞内受体的分布
J Cell Biol. 1984 Mar;98(3):1111-8. doi: 10.1083/jcb.98.3.1111.
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"In situ" determinations of apparent Km and Vmax of brush border disaccharidases along the villi of normal human jejunal biopsy specimens. A quantitative histochemical study.正常人类空肠活检标本绒毛上刷状缘双糖酶的表观米氏常数（Km）和最大反应速度（Vmax）的“原位”测定。一项定量组织化学研究。
Histochemistry. 1981;71(3):451-62. doi: 10.1007/BF00495885.
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Effects of intestinal adaptation on insulin binding to villus cell membranes.肠道适应性对胰岛素与绒毛细胞膜结合的影响。
Gut. 1987;28 Suppl(Suppl):57-62. doi: 10.1136/gut.28.suppl.57.