Phillips A D, Avigad S, Sacks J, Rice S J, France N E, Walker-Smith J A
Gut. 1980 Jan;21(1):44-8. doi: 10.1136/gut.21.1.44.
Electron microscopy was used to measure microvillous surface area in seven small intestinal biopsies showing secondary disaccharidase deficiency and in five biopsies having normal disaccharidase levels. There were significant reductions in microvillous surface area in the enzyme deficient group, although the microvilli were not severely damaged. Histological abnormality was not always present with disaccharidase deficiency. There was no significant difference in intraepithelial lymphocyte counts between the two groups.
采用电子显微镜测量了7例显示继发性双糖酶缺乏的小肠活检标本以及5例双糖酶水平正常的活检标本的微绒毛表面积。酶缺乏组的微绒毛表面积显著减少,尽管微绒毛并未受到严重损伤。双糖酶缺乏并不总是伴有组织学异常。两组之间的上皮内淋巴细胞计数无显著差异。