Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI, USA.
Vet Ophthalmol. 2020 May;23(3):418-435. doi: 10.1111/vop.12759. Epub 2020 Mar 20.
Electroretinography (ERG) is a commonly used technique to study retinal function in both clinical and research ophthalmology. ERG responses can be divided into component waveforms, analysis of which can provide insight into the health and function of different types and populations of retinal cells. In dogs, ERG has been used in the characterization of normal retinal function, as well as the diagnosis of retinal diseases and measuring effects of treatment. While many components of the recorded waveform are similar across species, dogs have several notable features that should be differentiated from the responses in humans and other animals. Additionally, modifications of standard protocols, such as changing flash frequency and stimulus color, and mathematical models of ERG waveforms have been used in studies of human retinal function but have been infrequently applied to visual electrophysiology in dogs. This review provides an overview of the origins and applications of ERG in addition to potential avenues for further characterization of responses in the dog.
视网膜电图(ERG)是一种常用于临床和研究眼科中研究视网膜功能的技术。ERG 反应可以分为组成波型,对其进行分析可以深入了解不同类型和群体的视网膜细胞的健康和功能。在犬中,ERG 已用于描述正常的视网膜功能,以及诊断视网膜疾病和测量治疗效果。虽然记录波形的许多成分在物种间相似,但犬有几个值得注意的特征,与人和其他动物的反应不同。此外,改变闪光频率和刺激颜色等标准协议的修改以及 ERG 波形的数学模型已用于人类视网膜功能的研究中,但在犬的视觉电生理学中很少应用。本综述概述了 ERG 的起源和应用,以及进一步描述犬反应的潜在途径。