Div. Telemic, Department of Electrical Engineering (ESAT), KU Leuven, Kasteelpark Arenberg 10, Box 2444, 3001 Leuven, Belgium.
IMEC, Kapeldreef 75, 3001 Heverlee, Belgium.
Sensors (Basel). 2020 Mar 18;20(6):1687. doi: 10.3390/s20061687.
This work presents a novel platform conceived as an interconnect box (ICB) that brings high-frequency signals from microwave instruments to consumable lab-on-a-chip devices. The ICB can be connected to instruments with a standard coaxial connector and to consumable chips by introducing a spring-levered interface with elastomer conductive pins. With the spring-system, microwave-microfluidic chips can be mounted reliably on the setup in a couple of seconds. The high-frequency interface within the ICB is protected from the environment by an enclosure having a single slit for mounting the chip. The stability and repeatability of the contact between the ICB and inserted consumable chips are investigated to prove the reliability of the proposed ICB. Given the rapid interconnecting of chips using the proposed ICB, five different interdigital capacitor (IDC) designs having the same sensing area were investigated for dielectric permittivity extraction of liquids. The designed IDCs, embedded in a polydimethylsiloxane (PDMS) channel, were fabricated with a lift-off gold patterning technology on a quartz substrate. Water-Isopropanol (IPA) mixtures with different volume fractions were flushed through the channel over IDCs and sensed based on the measured reflection coefficients. Dielectric permittivity was extracted using permittivity extraction techniques, and fitted permittivity data shows good agreement with literature from 100 to 25 GHz.
这项工作提出了一种新颖的平台,设计为互连盒(ICB),可将微波仪器的高频信号传输到消耗型片上实验室设备。ICB 可以通过引入带有弹性导电销的弹簧杠杆接口与带有标准同轴连接器的仪器以及消耗型芯片连接。通过弹簧系统,可以在几秒钟内可靠地将微波微流控芯片安装在设置上。ICB 内的高频接口通过带有单个狭缝的外壳与环境隔离,用于安装芯片。研究了 ICB 和插入的消耗型芯片之间接触的稳定性和可重复性,以证明所提出的 ICB 的可靠性。鉴于使用所提出的 ICB 快速互连芯片,研究了五个具有相同感应面积的叉指电容器(IDC)设计,以提取液体的介电常数。设计的 IDC 嵌入在聚二甲基硅氧烷(PDMS)通道中,使用石英衬底上的剥离金图案化技术制造。将不同体积分数的水-异丙醇(IPA)混合物通过 IDC 冲洗通道,并根据测量的反射系数进行感应。使用介电常数提取技术提取介电常数,拟合介电常数数据在 100 至 25GHz 范围内与文献数据吻合良好。