Department of Cellular Pathology, Imperial College London NHS Trust, London, UK
Department of Histopathology, GKT, Medical school in London, London, UK.
J Clin Pathol. 2020 May;73(5):239-242. doi: 10.1136/jclinpath-2020-206522. Epub 2020 Mar 20.
The severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) outbreak in Wuhan, China has now spread to many countries across the world including the UK with an increasing death toll. This will inevitably lead to an increase in the number of suspected coronavirus disease 2019 (COVID-19)-related deaths at autopsy. The Royal College of Pathologists has responded to this concern with the release of a briefing on autopsy practice relating to COVID-19. The following article is a summary and interpretation of these guidelines. It includes a description of hazard group 3 organisms, the category to which SARS-CoV-2 has been assigned, a brief description of what is currently known about the pathological and autopsy findings in COVID-19, a summary of the recommendations for conducting autopsies in suspected COVID-19 cases and the techniques for making the diagnosis at autopsy. It concludes by considering the clinicopathological correlation and notification of such cases.
中国武汉的严重急性呼吸综合征（SARS）-冠状病毒-2（CoV-2）爆发现已蔓延至包括英国在内的世界许多国家，死亡人数不断增加。这不可避免地会导致尸检中与 2019 年冠状病毒病（COVID-19）相关的疑似死亡人数增加。皇家病理学家学院针对这一关切发布了一份有关 COVID-19 尸检实践的简报。以下文章是对这些指南的总结和解释。它包括对危害组 3 生物体的描述，SARS-CoV-2 被归为该组，简要描述了目前对 COVID-19 的病理和尸检发现的了解，对疑似 COVID-19 病例进行尸检的建议摘要以及尸检时做出诊断的技术。最后，它考虑了临床病理相关性和此类病例的通报。
