Park Nicollet Contact Dermatitis Clinic, Minneapolis, Minnesota.
University of Minnesota Medical School, Minneapolis, Minnesota.
Pediatr Dermatol. 2020 Jul;37(4):745-747. doi: 10.1111/pde.14147. Epub 2020 Mar 20.
Isothiazolinones, preservatives including methylisothiazolinone (MI), methylchloroisothiazolinone/methylisothiazolinone (MCI/MI), benzisothiazolinone (BIT), and octylisothiazolinone (OIT), are notorious contact allergens. Pediatric dermatologists are familiar with these preservatives in personal care products, homemade slime recipes, and wet wipes. We present a novel source of MI declared in nail polish marketed to children.
异噻唑啉酮类,包括甲基异噻唑啉酮(MI)、甲基氯异噻唑啉酮/甲基异噻唑啉酮(MCI/MI)、苯并异噻唑啉酮(BIT)和辛基异噻唑啉酮(OIT),是臭名昭著的接触过敏原。儿科皮肤科医生熟悉这些防腐剂在个人护理产品、自制史莱姆食谱和湿纸巾中的应用。我们提出了一种新的 MI 来源,即在儿童指甲油中宣称的 MI。