Departamento e Instituto de Psiquiatria, Hospital das Clínicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, Rua Dr. Ovidio Pires de Campos 785, 3rd floor, São Paulo, SP 05403-010, Brazil.
Departamento e Instituto de Psiquiatria, Hospital das Clínicas (HCFMUSP), Faculdade de Medicina, Universidade de São Paulo, Rua Dr. Ovidio Pires de Campos 785, 3rd floor, São Paulo, SP 05403-010, Brazil.
Psychiatry Res. 2020 May;287:112914. doi: 10.1016/j.psychres.2020.112914. Epub 2020 Mar 18.
We conducted a randomized controlled trial to assess the effectiveness of social skills training (SST) in improving negative symptoms in patients with treatment-resistant schizophrenia with predominantly negative symptoms. Patients were randomized to receive SST (n = 29) or to a control group (n = 33), in a 20-week program with weekly group sessions. Patients were assessed at baseline, post-treatment (20 weeks) and 6-month follow-up with the Positive and Negative Syndrome Scale. There was no significant improvement in the negative symptoms in either group, at any timepoint. Caution is warranted to interpret the results due to small sample size.
我们进行了一项随机对照试验，以评估社交技能训练（SST）在改善以阴性症状为主的治疗抵抗性精神分裂症患者的阴性症状方面的有效性。患者被随机分配到 SST 组（n=29）或对照组（n=33），接受为期 20 周的每周一次小组治疗。患者在基线、治疗后（20 周）和 6 个月随访时使用阳性和阴性症状量表进行评估。在任何时间点，两组的阴性症状均无显著改善。由于样本量小，结果的解释需要谨慎。
