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PoEMs edit breast cancer outcome.

作者信息

Bieniasz-Krzywiec Pawel, Mazzone Massimiliano

机构信息

Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, VIB, Leuven B3000, Belgium.

Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology, Department of Oncology, KU Leuven, Leuven B3000, Belgium.

出版信息

Aging (Albany NY). 2020 Feb 26;12(5):4045-4047. doi: 10.18632/aging.102870.

DOI:10.18632/aging.102870
PMID:32200358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7093187/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cb3/7093187/33d9ed5fac9f/aging-12-102870-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cb3/7093187/33d9ed5fac9f/aging-12-102870-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cb3/7093187/33d9ed5fac9f/aging-12-102870-g001.jpg

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PoEMs edit breast cancer outcome.经皮内镜下肌切开术(PoEMs)改善乳腺癌预后。 (注:你提供的原文信息似乎存在不完整或不准确的情况,“PoEMs”一般指经皮内镜下肌切开术,与乳腺癌没有直接关联,这里是按照字面意思翻译的,你可根据实际情况进一步确认。)
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本文引用的文献

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Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer.足突蛋白表达的巨噬细胞促进乳腺癌淋巴管生成和淋巴管浸润。
Cell Metab. 2019 Nov 5;30(5):917-936.e10. doi: 10.1016/j.cmet.2019.07.015. Epub 2019 Aug 22.
2
Intratumoral myeloid cells regulate responsiveness and resistance to antiangiogenic therapy.肿瘤内髓样细胞调节对抗血管生成治疗的反应性和抗性。
Cell Rep. 2015 Apr 28;11(4):577-91. doi: 10.1016/j.celrep.2015.03.055. Epub 2015 Apr 16.
3
Podoplanin: emerging functions in development, the immune system, and cancer.
足突蛋白:在发育、免疫系统和癌症中的新兴功能。
Front Immunol. 2012 Sep 12;3:283. doi: 10.3389/fimmu.2012.00283. eCollection 2012.
4
Tumour-infiltrating macrophages and clinical outcome in breast cancer.浸润肿瘤的巨噬细胞与乳腺癌的临床结局。
J Clin Pathol. 2012 Feb;65(2):159-63. doi: 10.1136/jclinpath-2011-200355. Epub 2011 Nov 2.
5
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.靶向 ANG2/TIE2 轴通过抑制血管生成和使促血管生成的髓样细胞的反弹失活来抑制肿瘤生长和转移。
Cancer Cell. 2011 Apr 12;19(4):512-26. doi: 10.1016/j.ccr.2011.02.005.
6
Lymphatic and blood vessels in basal and triple-negative breast cancers: characteristics and prognostic significance.基底型和三阴性乳腺癌中的淋巴管和血管:特征和预后意义。
Mod Pathol. 2011 Jun;24(6):774-85. doi: 10.1038/modpathol.2011.4. Epub 2011 Mar 4.
7
Sustained induction of ERK, protein kinase B, and p70 S6 kinase regulates cell spreading and formation of F-actin microspikes upon ligation of integrins by galectin-8, a mammalian lectin.哺乳动物凝集素半乳糖凝集素-8通过整合素连接持续诱导细胞外信号调节激酶、蛋白激酶B和p70核糖体蛋白S6激酶,可调节细胞铺展和F-肌动蛋白微刺的形成。
J Biol Chem. 2003 Apr 18;278(16):14533-42. doi: 10.1074/jbc.M207380200. Epub 2003 Feb 4.
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A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.一种涉及Src家族激酶、Cbl和PI-3激酶的β1整合素信号通路是巨噬细胞铺展和迁移所必需的。
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