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青少年 2 型糖尿病的外科治疗。

Surgical Treatment of Type 2 Diabetes Mellitus in Youth.

机构信息

Division of Endocrinology, Children's National Health System, Washington, DC, USA.

Division of Pediatric Surgery, Children's National Health System, Washington, DC, USA.

出版信息

Adv Exp Med Biol. 2021;1307:321-330. doi: 10.1007/5584_2020_511.

Abstract

Bariatric surgery is currently the most effective weight loss treatment of severe obesity and its associated comorbidities and is being increasingly used to treat children and adolescents with severe obesity, including those with Type 2 Diabetes (T2D). This review focuses on the conventional management of T2D in children and adolescents, comparison of various types of bariatric surgeries, effect of bariatric surgery on gastrointestinal physiology and metabolism, current literature on the use of bariatric surgery to treat youth with severe obesity and T2D, and the potential complications of bariatric surgery in this population.

摘要

减重手术目前是治疗重度肥胖及其相关并发症的最有效方法,越来越多地用于治疗患有重度肥胖的儿童和青少年,包括 2 型糖尿病(T2D)患者。本文主要综述儿童和青少年 T2D 的常规治疗方法,比较各种减重手术的类型,减重手术对胃肠道生理学和代谢的影响,目前关于使用减重手术治疗患有重度肥胖和 T2D 的青少年的文献,以及该人群中减重手术的潜在并发症。

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