米氮平治疗脑胶质母细胞瘤所致磨牙症：一例报告
Treatment of cerebral glioblastoma-caused bruxism with mirtazapine: a case report.
作者信息
Khosravi Mohsen
机构信息
Department of Psychiatry and Clinical Psychology, Baharan Psychiatric Hospital, Zahedan University of Medical Sciences, Zahedan, IR, 9813913777, Iran.
出版信息
JA Clin Rep. 2020 Mar 21;6(1):23. doi: 10.1186/s40981-020-00329-4.
Abstract
BACKGROUND
Bruxism refers to grind or gnash the opposing rows of upper and lower molar teeth. It is important to treat bruxism as a factor that can influence sleep quality, quality of life, and mental status in patients with malignancy.
CASE PRESENTATION
A 41-year-old male developed bruxism secondary to cerebral glioblastoma. L-dopa, gabapentin, clonazepam, clonidine, baclofen, buspirone, or propranolol were not effective. Mirtazapine, prescribed for side effects of chemotherapy, was effective for bruxism, which was disappeared within 3 weeks.
CONCLUSIONS
Mirtazapine was effective for treating bruxism as well as chemotherapy complications.
摘要
背景
磨牙症是指上下颌磨牙相互磨动或咬紧。将磨牙症作为影响恶性肿瘤患者睡眠质量、生活质量和精神状态的一个因素来治疗很重要。
病例报告
一名41岁男性因脑胶质母细胞瘤继发磨牙症。左旋多巴、加巴喷丁、氯硝西泮、可乐定、巴氯芬、丁螺环酮或普萘洛尔均无效。因化疗副作用而开具的米氮平对磨牙症有效，磨牙症在3周内消失。
结论
米氮平对治疗磨牙症以及化疗并发症均有效。
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J Oral Rehabil. 2018 Nov;45(11):837-844. doi: 10.1111/joor.12663. Epub 2018 Jun 21.
2
Association of sleep bruxism with oral health-related quality of life and sleep quality.磨牙症与口腔健康相关生活质量和睡眠质量的关系。
Clin Oral Investig. 2019 Jan;23(1):245-251. doi: 10.1007/s00784-018-2431-0. Epub 2018 Mar 27.
3
Survival in glioblastoma: a review on the impact of treatment modalities.胶质母细胞瘤的生存：关于治疗方式影响的综述
Clin Transl Oncol. 2016 Nov;18(11):1062-1071. doi: 10.1007/s12094-016-1497-x. Epub 2016 Mar 10.
4
The Last 10 Days of Patients With Glioblastoma: Assessment of Clinical Signs and Symptoms as well as Treatment.胶质母细胞瘤患者的最后10天：临床体征和症状评估以及治疗
Am J Hosp Palliat Care. 2016 Dec;33(10):985-988. doi: 10.1177/1049909115609295. Epub 2015 Oct 14.
5
Comparison of cerebral activity during teeth clenching and fist clenching: a functional magnetic resonance imaging study.紧咬牙与紧握拳时脑活动的比较：一项功能磁共振成像研究
Eur J Oral Sci. 2010 Dec;118(6):635-41. doi: 10.1111/j.1600-0722.2010.00784.x.
6
Taking up challenges at the interface of wear and tear.
J Dent Res. 2007 Feb;86(2):101-3. doi: 10.1177/154405910708600201.
7
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Brain Res Bull. 2004 Apr 30;63(3):237-41. doi: 10.1016/j.brainresbull.2004.02.007.
8
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CNS Drug Rev. 2001 Fall;7(3):249-64. doi: 10.1111/j.1527-3458.2001.tb00198.x.
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Eur J Neurosci. 2000 Mar;12(3):1079-95. doi: 10.1046/j.1460-9568.2000.00982.x.
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J Dent Res. 1988 Mar;67(3):597-601. doi: 10.1177/00220345880670031501.
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