Scuiller A, Pascart T, Bernard A, Oehler E
Service de médecine interne et polyvalente, centre hospitalier de Polynésie française, 98714 Pirae, Tahiti.
Service de rhumatologie, hôpital Saint-Philibert, université de Lille, 59462 Lomme cedex, France.
Rev Med Interne. 2020 Jun;41(6):396-403. doi: 10.1016/j.revmed.2020.02.014. Epub 2020 Mar 19.
Gout is a chronic disease due to the deposition of monosodium urate microcrystals in joints and tissues. Its incidence and prevalence are increasing worldwide in close relation with the epidemic of obesity and metabolic syndrome. Gout is related to chronic hyperuricemia that should be treated to ensure the reduction or even the disappearance of acute attacks ("gout flares") and to reduce the size and number of tophi. If arthritis of the first metatarsophalangeal joint is the most typical form, other joints may be affected, including the spine. Demonstration of urate microcrystals arthritis allows diagnosis of gout but, in the absence of possibility of performing joint puncture, imaging may be useful for providing complementary diagnostic elements. Appropriate care is essential to reduce the number of flares and the evolution towards gouty arthropathy but also in terms of public health in order to reduce costs related to this pathology.
痛风是一种由于单钠尿酸盐微晶在关节和组织中沉积而导致的慢性疾病。其发病率和患病率在全球范围内呈上升趋势,与肥胖和代谢综合征的流行密切相关。痛风与慢性高尿酸血症有关,应进行治疗以确保减少甚至消除急性发作(“痛风发作”),并减小痛风石的大小和数量。如果第一跖趾关节关节炎是最典型的形式,其他关节也可能受到影响,包括脊柱。尿酸盐微晶关节炎的证实有助于痛风的诊断,但在无法进行关节穿刺的情况下,影像学检查可能有助于提供补充诊断依据。适当的治疗对于减少发作次数以及预防痛风性关节病的进展至关重要,同时从公共卫生角度来看,对于降低与这种疾病相关的成本也很重要。