Laboratory of Nutrition, Exercise and Health (LaNES), School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil.
School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil.
Clin Nutr. 2020 Nov;39(11):3434-3441. doi: 10.1016/j.clnu.2020.03.001. Epub 2020 Mar 9.
Muscle strength is a predictor of mortality in older adults and some dietary components are associated with this variable; however, little is known about the association between omega-3 fatty acids (ω-3) intake and strength in older adults.
To assess whether ω-3 intake is associated with muscle strength in individuals over 50 years. We also aimed to evaluate whether an isocaloric substitution of dietary fatty acids types by ω-3 intake could be associated with muscle strength.
This study included older adults aged from 50 to 85 y, from National Health and Nutrition Examination Survey (NHANES) 1999-2000 and 2001-2002. A total of 2141 individuals (1119 men and 1022 women) were evaluated and provided complete and reliable dietary intake and isokinetic strength of the knee extensors (peak force) data. Linear regression analysis was conducted without (Model 1) and with adjustments (Model 2). Isocaloric substitution analysis was performed to evaluate whether the substitution of polyunsaturated (excluding ω-3), monounsaturated, saturated fats and ω-6 by consumption of ω-3 is associated with strength.
Total ω-3, docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and alpha-linolenic acid (ALA) intakes were positively associated with peak force in men (Model 1). However, after the adjustments for confounders (Model 2), only total ω-3 intake remained significant. Ω-3 intake was not associated with strength in women. The isocaloric substitution of saturated, polyunsaturated, monounsaturated fats and ω-6 by ω-3 was not associated with peak force.
The intake of total ω-3 was positively associated with muscle strength in older men, but not in older women. In addition, the substitution of other fatty acids by ω-3 intake was not associated with strength.
肌肉力量是老年人死亡率的预测指标，某些饮食成分与该变量相关；然而，人们对ω-3 脂肪酸（ω-3）摄入与老年人力量之间的关系知之甚少。
评估 ω-3 摄入是否与 50 岁以上人群的肌肉力量相关。我们还旨在评估通过 ω-3 摄入对饮食脂肪酸类型进行等热量替代是否与肌肉力量相关。
本研究纳入了 1999-2000 年和 2001-2002 年全国健康与营养调查（NHANES）中年龄在 50 至 85 岁的老年人。共评估了 2141 名个体（1119 名男性和 1022 名女性），并提供了完整且可靠的饮食摄入和膝关节伸肌等速力量（峰值力）数据。进行了线性回归分析，未进行（模型 1）和进行了调整（模型 2）。进行等热量替代分析，以评估通过消费 ω-3 替代多不饱和（不包括 ω-3）、单不饱和、饱和脂肪和 ω-6 是否与力量相关。
男性中，总 ω-3、二十二碳六烯酸（DHA）、二十碳五烯酸（EPA）和α-亚麻酸（ALA）的摄入量与峰值力呈正相关（模型 1）。然而，在调整混杂因素后（模型 2），只有总 ω-3 摄入量仍然具有统计学意义。ω-3 摄入量与女性的力量无关。用 ω-3 替代饱和、多不饱和、单不饱和脂肪和 ω-6 与峰值力无关。
总 ω-3 摄入与老年男性的肌肉力量呈正相关，但与老年女性的肌肉力量无关。此外，用 ω-3 摄入替代其他脂肪酸与力量无关。
