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[Dihydro-5,6-imidazo[2,1-b]thiazoles, dihydro-2,3-imidazo[2,1-b]benzothiazoles, analogs of levamisole].

作者信息

Amarouch H, Loiseau P R, Bonnafous M, Caujolle R, Payard M, Loiseau P M, Bories C, Gayral P

机构信息

Département de Chimie Pharmaceutique, Faculté de Pharmacie, Toulouse, France.

出版信息

Farmaco Sci. 1988 May;43(5):421-37.

PMID:3220127
Abstract

New compounds containing 5,6-dihydro imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro imidazo[2,1-b]thiazole and 2,3-dihydro imidazo[2,1-b]benzothiazole rings, substituted by heterocycles analogue to chromones, were synthesized and screened against three nematodes, in vitro. The results indicate moderate anthelmintic properties, compared to levamisole; nevertheless, some products exhibit a significant degree of activity.

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