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2020 年 1 月 31 日至 3 月 1 日法国马赛传染病转诊医院疑似 COVID-19 病例的快速病毒诊断和门诊管理:呼吸道病毒快照。

Rapid viral diagnosis and ambulatory management of suspected COVID-19 cases presenting at the infectious diseases referral hospital in Marseille, France, - January 31st to March 1st, 2020: A respiratory virus snapshot.

机构信息

IHU-Méditerranée Infection, Marseille, France; Aix Marseille Univ, IRD, APHM, MEPHI, Marseille, France.

IHU-Méditerranée Infection, Marseille, France.

出版信息

Travel Med Infect Dis. 2020 Jul-Aug;36:101632. doi: 10.1016/j.tmaid.2020.101632. Epub 2020 Mar 20.

Abstract

BACKGROUND

Rapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases.

METHOD

We managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. Rapid viral detection was performed on sputum and nasopharyngeal samples.

RESULTS

Over our study period, no SARS-CoV-2 was detected. Results were obtained within approximately 3 h of the arrival of patient samples at the laboratory. Other viral infections were identified in 49% of the patients, with most common pathogens being influenza A and B viruses, rhinovirus, metapneumovirus and common coronaviruses, notably HKU1 and NL63.

CONCLUSION

Early recognition of COVID-19 is critical to isolate confirmed cases and prevent further transmission. Early rule-out of COVID-19 allows public health containment measures to be adjusted by reducing the time spent in isolation.

摘要

背景

需要快速的病毒学诊断来限制疑似 COVID-19 病例的隔离时间。

方法

我们通过快速护理回路管理法国马赛传染病参考医院的前 280 例疑似 COVID-19 患者,并进行病毒学诊断。对痰液和鼻咽样本进行快速病毒检测。

结果

在我们的研究期间,未检测到 SARS-CoV-2。患者样本到达实验室后约 3 小时即可获得结果。49%的患者被诊断为其他病毒感染,最常见的病原体是甲型和乙型流感病毒、鼻病毒、副流感病毒和常见的冠状病毒,尤其是 HKU1 和 NL63。

结论

早期识别 COVID-19 对于隔离确诊病例和防止进一步传播至关重要。早期排除 COVID-19 可以通过减少隔离时间来调整公共卫生控制措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41a7/7102626/9950f8cce133/gr1_lrg.jpg

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