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正电子发射断层扫描-计算机断层扫描在检测治疗后残留肝细胞癌中的应用:系列病例报告

Utility of positron emission tomography-computed tomography scan in detecting residual hepatocellular carcinoma post treatment: Series of case reports.

作者信息

Cheng Jason T, Tan Nelly E, Volk Michael L

机构信息

Transplantation Institute, Loma Linda University Medical Center, San Bernardino, CA 92408, United States.

Department of Radiology, Loma Linda University Medical Center, Loma Linda, CA 92354, United States.

出版信息

World J Gastrointest Oncol. 2020 Mar 15;12(3):358-364. doi: 10.4251/wjgo.v12.i3.358.

Abstract

BACKGROUND

Multi-phase computed tomography (CT) or magnetic resonance imaging (MRI) has been the standard of care for hepatocellular carcinoma (HCC) diagnosis for years.

CASE SUMMARY

We report a case series of four patients in whom positron emission tomography-computed tomography (PET-CT) scan complemented the conventional CT/MRI scans in evaluating treatment response. In these four cases the conventional multi-phase CT and MRI failed to identify residual HCC disease post-treatment, while PET-CT complemented and aided in treatment response evaluation. In each case, the addition of PET-CT identified and located residual HCC disease, allowed retreatment, and altered medical management.

CONCLUSION

This case series suggests that PET-CT should perhaps play a role in the HCC management algorithm, in addition to the conventional contrast-enhanced multi-phase scans.

摘要

背景

多年来,多期计算机断层扫描(CT)或磁共振成像(MRI)一直是肝细胞癌(HCC)诊断的标准治疗方法。

病例摘要

我们报告了一个包含四名患者的病例系列,其中正电子发射断层扫描-计算机断层扫描(PET-CT)扫描在评估治疗反应方面补充了传统的CT/MRI扫描。在这四个病例中,传统的多期CT和MRI未能识别治疗后残留的HCC疾病,而PET-CT补充并有助于治疗反应评估。在每个病例中,PET-CT的加入识别并定位了残留的HCC疾病,允许再次治疗,并改变了医疗管理。

结论

这个病例系列表明,除了传统的对比增强多期扫描外,PET-CT或许应在HCC管理算法中发挥作用。

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