• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用于肺动脉高压患者静脉输注曲前列尼尔的完全植入式泵的流速变化

Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension.

作者信息

Richter Manuel J, Harutyunova Satenik, Bollmann Tom, Classen Simon, Fuge Jan, Gall Henning, Gerhardt Felix, Ghofrani Hossein A, Gunkel Hartmut, Grünig Ekkehard, Halank Michael, Heine Alexander, Klose Hans, Lange Tobias J, Neurohr Claus, Nickolaus Kai, Opitz Christian F, Rosenkranz Stephan, Seyfarth Hans-Jürgen, Tello Khodr, Ewert Ralf, Olsson Karen M

机构信息

Department of Pneumology, Kerckhoff Heart, Rheuma and Thoracic Center, Bad Nauheim, Germany.

Department of Internal Medicine, Justus Liebig University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.

出版信息

Pulm Circ. 2020 Mar 13;10(1):2045894020910136. doi: 10.1177/2045894020910136. eCollection 2020 Jan-Mar.

DOI:10.1177/2045894020910136
PMID:32206306
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7074510/
Abstract

Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.

摘要

植入式输液泵可能会提高静脉注射曲前列尼尔治疗肺动脉高压的便利性和安全性。LENUS Pro®泵（在欧洲获批）具有固定流速。基于126台泵和2853次补充装液，我们回顾性分析了2010年9月至2018年9月期间的实际流速。三年后明显出现了相关的流速差异；因此，流速监测和剂量调整是必不可少的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/badc/7074510/2efcc1e5c930/10.1177_2045894020910136-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/badc/7074510/2efcc1e5c930/10.1177_2045894020910136-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/badc/7074510/2efcc1e5c930/10.1177_2045894020910136-fig1.jpg

相似文献

1
Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension.用于肺动脉高压患者静脉输注曲前列尼尔的完全植入式泵的流速变化
Pulm Circ. 2020 Mar 13;10(1):2045894020910136. doi: 10.1177/2045894020910136. eCollection 2020 Jan-Mar.
2
Intravenous treprostinil via an implantable pump in pediatric pulmonary arterial hypertension.通过植入式泵静脉输注曲前列尼尔治疗小儿肺动脉高压
Pulm Circ. 2019 Jan-Mar;9(1):2045894018788846. doi: 10.1177/2045894018788846. Epub 2018 Jun 26.
3
Implantable LENUS pro pump for treprostinil infusion in three pediatric patients.在三名儿科患者中植入 LENUS pro 泵进行曲前列尼尔输注。
Pediatr Pulmonol. 2020 May;55(5):1254-1258. doi: 10.1002/ppul.24707. Epub 2020 Mar 9.
4
Unexpected Acceleration in Treprostinil Delivery Administered by a Lenus Pro® Implantable Pump in Two Patients Treated for Pulmonary Arterial Hypertension.两名接受肺动脉高压治疗的患者使用Lenus Pro®植入式泵输注曲前列尼尔时出现意外加速。
Front Med (Lausanne). 2020 Oct 30;7:539707. doi: 10.3389/fmed.2020.539707. eCollection 2020.
5
An implantable pump Lenus pro® in the treatment of pulmonary arterial hypertension with intravenous treprostinil.植入式 Lenus pro® 泵联合静脉注射曲前列尼尔治疗肺动脉高压。
BMC Pulm Med. 2017 Dec 2;17(1):162. doi: 10.1186/s12890-017-0474-7.
6
Intravenous treprostinil infusion via a fully implantable pump for pulmonary arterial hypertension.经全植入式输液泵静脉输注曲前列尼尔治疗肺动脉高压。
Clin Res Cardiol. 2017 Oct;106(10):776-783. doi: 10.1007/s00392-017-1114-1. Epub 2017 Apr 20.
7
Long-term experience with implantable infusion pumps for intravenous treprostinil in pulmonary arterial hypertension-procedural safety and system-related complications.肺动脉高压患者使用植入式输注泵静脉输注曲前列尼尔的长期经验——操作安全性及与系统相关的并发症
Pulm Circ. 2020 Nov 30;10(4):2045894020970830. doi: 10.1177/2045894020970830. eCollection 2020 Oct-Dec.
8
Procedural safety of a fully implantable intravenous prostanoid pump for pulmonary hypertension.用于肺动脉高压的完全植入式静脉前列腺素泵的操作安全性
Clin Res Cardiol. 2017 Mar;106(3):174-182. doi: 10.1007/s00392-016-1037-2. Epub 2016 Sep 26.
9
Long-term safety and outcome of intravenous treprostinil via an implanted pump in pulmonary hypertension.肺动脉高压患者经植入式输液港输注曲前列尼尔的长期安全性和结局。
J Heart Lung Transplant. 2018 Oct;37(10):1235-1244. doi: 10.1016/j.healun.2018.06.006. Epub 2018 Jun 21.
10
Treprostinil Administered to Treat Pulmonary Arterial Hypertension Using a Fully Implantable Programmable Intravascular Delivery System: Results of the DelIVery for PAH Trial.使用完全植入式可编程血管内给药系统给予曲前列尼尔治疗肺动脉高压：PAH试验的DelIVery研究结果
Chest. 2016 Jul;150(1):27-34. doi: 10.1016/j.chest.2015.11.005. Epub 2016 Jan 13.

引用本文的文献

1
Periprocedural safety and outcome after pump implantation for intravenous treprostinil administration in patients with pulmonary arterial hypertension.肺动脉高压患者静脉注射曲前列尼尔泵植入围手术期安全性和结局。
BMC Pulm Med. 2021 May 15;21(1):164. doi: 10.1186/s12890-021-01541-3.
2
Long-term experience with implantable infusion pumps for intravenous treprostinil in pulmonary arterial hypertension-procedural safety and system-related complications.肺动脉高压患者使用植入式输注泵静脉输注曲前列尼尔的长期经验——操作安全性及与系统相关的并发症
Pulm Circ. 2020 Nov 30;10(4):2045894020970830. doi: 10.1177/2045894020970830. eCollection 2020 Oct-Dec.
3

本文引用的文献

1
Long-term results of the DelIVery for Pulmonary Arterial Hypertension trial.肺动脉高压分娩试验的长期结果
Pulm Circ. 2019 Nov 5;9(4):2045894019878615. doi: 10.1177/2045894019878615. eCollection 2019 Oct-Dec.
2
Intravenous treprostinil as an add-on therapy in patients with pulmonary arterial hypertension.静脉注射曲前列尼尔作为肺动脉高压患者的附加治疗。
J Heart Lung Transplant. 2019 Jul;38(7):748-756. doi: 10.1016/j.healun.2019.05.002. Epub 2019 May 7.
3
Long-term safety and outcome of intravenous treprostinil via an implanted pump in pulmonary hypertension.
Unexpected Acceleration in Treprostinil Delivery Administered by a Lenus Pro® Implantable Pump in Two Patients Treated for Pulmonary Arterial Hypertension.
两名接受肺动脉高压治疗的患者使用Lenus Pro®植入式泵输注曲前列尼尔时出现意外加速。
Front Med (Lausanne). 2020 Oct 30;7:539707. doi: 10.3389/fmed.2020.539707. eCollection 2020.
肺动脉高压患者经植入式输液港输注曲前列尼尔的长期安全性和结局。
J Heart Lung Transplant. 2018 Oct;37(10):1235-1244. doi: 10.1016/j.healun.2018.06.006. Epub 2018 Jun 21.
4
Intravenous treprostinil via an implantable pump in pediatric pulmonary arterial hypertension.通过植入式泵静脉输注曲前列尼尔治疗小儿肺动脉高压
Pulm Circ. 2019 Jan-Mar;9(1):2045894018788846. doi: 10.1177/2045894018788846. Epub 2018 Jun 26.
5
An implantable pump Lenus pro® in the treatment of pulmonary arterial hypertension with intravenous treprostinil.植入式 Lenus pro® 泵联合静脉注射曲前列尼尔治疗肺动脉高压。
BMC Pulm Med. 2017 Dec 2;17(1):162. doi: 10.1186/s12890-017-0474-7.
6
Intravenous treprostinil infusion via a fully implantable pump for pulmonary arterial hypertension.经全植入式输液泵静脉输注曲前列尼尔治疗肺动脉高压。
Clin Res Cardiol. 2017 Oct;106(10):776-783. doi: 10.1007/s00392-017-1114-1. Epub 2017 Apr 20.
7
Procedural safety of a fully implantable intravenous prostanoid pump for pulmonary hypertension.用于肺动脉高压的完全植入式静脉前列腺素泵的操作安全性
Clin Res Cardiol. 2017 Mar;106(3):174-182. doi: 10.1007/s00392-016-1037-2. Epub 2016 Sep 26.
8
Treprostinil Administered to Treat Pulmonary Arterial Hypertension Using a Fully Implantable Programmable Intravascular Delivery System: Results of the DelIVery for PAH Trial.使用完全植入式可编程血管内给药系统给予曲前列尼尔治疗肺动脉高压：PAH试验的DelIVery研究结果
Chest. 2016 Jul;150(1):27-34. doi: 10.1016/j.chest.2015.11.005. Epub 2016 Jan 13.
9
Treatment of patients with pulmonary arterial hypertension at the time of death or deterioration to functional class IV: insights from the REVEAL Registry.肺动脉高压患者在死亡时或病情恶化为IV级功能状态时的治疗：来自REVEAL注册研究的见解
J Heart Lung Transplant. 2013 Nov;32(11):1114-22. doi: 10.1016/j.healun.2013.08.010. Epub 2013 Sep 10.
10
A case series of patients with severe pulmonary hypertension receiving an implantable pump for intravenous prostanoid therapy.一组接受植入式泵进行静脉前列腺素治疗的重度肺动脉高压患者病例系列。
Am J Respir Crit Care Med. 2012 Dec 1;186(11):1196-8. doi: 10.1164/ajrccm.186.11.1196.