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老年患者多节段脊柱融合术后的疗效及生活质量改善情况

Outcomes and Quality of Life Improvement After Multilevel Spinal Fusion in Elderly Patients.

作者信息

Ibrahim John M, Singh Paramjit, Beckerman Daniel, Hu Serena S, Tay Bobby, Deviren Vedat, Burch Shane, Berven Sigurd H

机构信息

University of California-San Francisco, San Francisco, CA, USA.

Stanford University Medical Center, Palo Alto, CA, USA.

出版信息

Global Spine J. 2020 Apr;10(2):153-159. doi: 10.1177/2192568219849393. Epub 2019 May 19.

Abstract

STUDY DESIGN

Retrospective case series.

OBJECTIVES

Both the rate and complexity of spine surgeries in elderly patients has increased. This study reports the outcomes of multilevel spine fusion in elderly patients and provides evidence on the appropriateness of complex surgery in elderly patients.

METHODS

We identified 101 patients older than70 years who had ≥5 levels of fusion. Demographic, medical, and surgical data, and change between preoperative and >500 days postoperative health survey scores were collected. Health surveys were visual analogue scale (VAS), EuroQoL 5 Dimensions (EQ-5D), Oswestry Disability Index (ODI), Scoliosis Research Society questionnaire (SRS-30), and Short Form health survey (SF-12) (physical composite score [PCS] and mental composite score [MCS]). Minimal clinically important differences (MCIDs) were defined for each survey.

RESULTS

Complications included dural tears (19%), intensive care unit admission (48%), revision surgery within 2 to 5 years (24%), and death within 2 to 5 years (16%). The percentage of patients who reported an improvement in health-related quality of life (HRQOL) of at least an MCID was: VAS Back 69%; EQ-5D 41%; ODI 58%; SRS-30 45%; SF-12 PCS 44%; and SF-12 MCS 48%. Improvement after a primary surgery, as compared with a revision, was on average 13 points higher in ODI ( = .007). Patients who developed a surgical complication averaged an improvement 11 points lower on ODI ( = .042). Patients were more likely to find improvement in their health if they had a lower American Society of Anesthesiologists or Charlson Comorbidity Index score or a higher metabolic equivalent score.

CONCLUSIONS

In multilevel surgery in patients older than 70 years, complications are common, and on average 77% of patients attain some improvement, with 51% reaching an MCID. Physiological status is a stronger predictor of outcomes than chronological age.

摘要

研究设计

回顾性病例系列研究。

目的

老年患者脊柱手术的发生率和复杂性均有所增加。本研究报告老年患者多节段脊柱融合术的结果,并为老年患者进行复杂手术的适宜性提供证据。

方法

我们确定了101例年龄大于70岁且融合节段≥5个节段的患者。收集了人口统计学、医学和手术数据,以及术前和术后>500天健康调查评分的变化。健康调查包括视觉模拟量表(VAS)、欧洲五维健康量表(EQ-5D)、Oswestry功能障碍指数(ODI)、脊柱侧弯研究学会问卷(SRS-30)和简短健康调查问卷(SF-12)(身体综合评分[PCS]和精神综合评分[MCS])。为每项调查定义了最小临床重要差异(MCID)。

结果

并发症包括硬脊膜撕裂(19%)、入住重症监护病房(48%)、2至5年内翻修手术(24%)和2至5年内死亡(16%)。报告健康相关生活质量(HRQOL)至少改善一个MCID的患者百分比为:VAS背部69%;EQ-5D 41%;ODI 58%;SRS-30 45%;SF-12 PCS 44%;SF-12 MCS 48%。与翻修手术相比,初次手术后ODI平均改善高13分(P = .007)。发生手术并发症的患者ODI平均改善低11分(P = .042)。如果美国麻醉医师协会或Charlson合并症指数评分较低或代谢当量评分较高,患者更有可能在健康方面有所改善。

结论

在70岁以上患者的多节段手术中,并发症很常见,平均77%的患者有一定改善,51%达到MCID。生理状态比实际年龄更能预测手术结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/634d/7076597/5ff0e1df7b99/10.1177_2192568219849393-fig1.jpg

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