Rodriguez Then Francisca S, Jackson Jonathan, Ware Caitlin, Churchyard Rebekah, Hanseeuw Bernard
German Center for Neurodegenerative Diseases (DZNE), RG Psychosocial Epidemiology & Public Health, Greifswald, Germany.
Edward R. Roybal Institute on Aging, University of Southern California, Los Angeles, CA, USA.
J Alzheimers Dis Rep. 2020 Feb 12;4(1):39-48. doi: 10.3233/ADR-180070.
Dementia, of which the most frequent form is Alzheimer's disease, is a chronic and terminal condition with multi-factorial causes and numerous consequences on a patient's life. Combining perspectives from different disciplines seems necessary for unraveling dementia's entangled issues. Current dementia management is a multidisciplinary effort; however, integrating different disciplines as a holistic treatment process is often hindered due to different responsibilities, various conceptual approaches, and distinctive research methods. With this paper, we raise some of the challenges that need to be addressed in order to initiate an interdisciplinary or even transdisciplinary research agenda. We also outline recommendations on how to integrate multiple disciplinary perspectives in dementia care and research. We see opportunities for young investigators to draw from different fields of research in dementia as their research focus is still developing. By establishing common objectives with investigators from other fields, we can pursue the goal of improving treatment and care as a team-meaning accomplishing different tasks but sharing a common purpose. It is necessary to address the communication between fields that limits the understanding of connections between cognitive symptoms, biological processes, treatment, lifestyle, and care giving in order to reach the aim of developing a holistic, person-centered, patient-first approach. Associating biomedical research to field experience from care professionals and the study of human science will promote a more independent, social, and sustainable lifestyle for people with dementia.
痴呆症,其中最常见的形式是阿尔茨海默病,是一种慢性终末期疾病,病因多因素,对患者生活有诸多影响。整合不同学科的观点似乎对于理清痴呆症错综复杂的问题是必要的。当前的痴呆症管理是一项多学科的工作;然而,由于职责不同、概念方法各异以及研究方法有别,将不同学科整合为一个整体治疗过程往往受到阻碍。在本文中,我们提出了一些为启动跨学科甚至跨领域研究议程而需要解决的挑战。我们还概述了关于如何在痴呆症护理和研究中整合多个学科观点的建议。我们看到年轻研究人员有机会从痴呆症研究的不同领域汲取经验,因为他们的研究重点仍在发展中。通过与其他领域的研究人员确立共同目标,我们可以作为一个团队追求改善治疗和护理的目标——即完成不同任务但共享一个共同目的。有必要解决各领域之间的沟通问题,这种沟通限制了对认知症状、生物过程、治疗、生活方式和护理之间联系的理解,以便实现发展一种整体的、以人为本、患者至上方法的目标。将生物医学研究与护理专业人员的实践经验以及人文科学研究相结合,将为痴呆症患者促进更独立、社交化和可持续的生活方式。