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摩洛哥东部的患者对生物库的认知和态度。

Patients' Knowledge and Attitude Toward Biobanks in Eastern Morocco.

机构信息

Genetics Unit, Medical Sciences Research Laboratory, Faculty of Medicine and Pharmacy of Oujda, University Mohammed Premier, Oujda, Morocco.

Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, University Mohammed Premier, Oujda, Morocco.

出版信息

Biopreserv Biobank. 2020 Jun;18(3):189-195. doi: 10.1089/bio.2019.0047. Epub 2020 Mar 24.

Abstract

To integrate biobanks into the Moroccan health system and to promote biobanks-based research projects, it is necessary to explore the knowledge of patients, their attitudes toward biobanks, and the reasons that motivate them to participate in biobanks. Face-to-face interviews were conducted with patients, and data were analyzed using One thousand one hundred thirty-three questionnaires were completed. The mean age of patients was 47.74 years (SD 15.26 years). More women (69%) were involved in this survey. Of the respondents, 97% had never heard of the term "biobanks." Knowledge of biobanks varied significantly with respondents' education level. Overall, 80.7% of the participants ( = 914) expressed their willingness to participate in biobanking through donation of biospecimens associated with personnel and health data. Willingness to participate in biobanks was significantly associated with gender and age. We found that the main barriers to participation in biobanks were the lack of trust in biomedical research and concerns about privacy. When asked about the preferred type of consent, the majority of patients (75%) opted for a one-time consent. Despite the lack of knowledge of biobanks among patients in Eastern Morocco, the majority of them expressed willingness to participate in biobanking through donation of biospecimens. However, active participation depended upon a number of factors, notably, the trust in biomedical research and privacy. Therefore, more efforts are needed to increase awareness and promote wider participation in biobanking.

摘要

为了将生物库融入摩洛哥卫生系统并促进基于生物库的研究项目,有必要探索患者的知识、他们对生物库的态度以及促使他们参与生物库的原因。我们对患者进行了面对面的访谈,并使用 对 1133 份问卷进行了分析。患者的平均年龄为 47.74 岁(SD 15.26 岁)。这项调查中女性(69%)居多。受访者中,97%从未听说过“生物库”一词。对生物库的了解与受访者的教育水平差异显著。总体而言,80.7%的参与者(即 914 人)表示愿意通过捐献与人员和健康数据相关的生物样本参与生物库。参与生物库的意愿与性别和年龄显著相关。我们发现,参与生物库的主要障碍是对生物医学研究的信任度不足和对隐私的担忧。当被问及他们更喜欢的同意类型时,大多数患者(75%)选择一次性同意。尽管摩洛哥东部的患者对生物库了解甚少,但大多数人表示愿意通过捐献生物样本参与生物库。然而,积极参与取决于许多因素,特别是对生物医学研究和隐私的信任。因此,需要做出更多努力来提高认识并促进更广泛地参与生物库。

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