Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, Changsha, China.
Hunan Key Laboratory of Ophthalmology, Central South University, Changsha, China.
Front Public Health. 2022 Nov 23;10:1025775. doi: 10.3389/fpubh.2022.1025775. eCollection 2022.
The biobank is an extraordinary aid to research and scientific progress. Public involvement in biobanks, necessary for their development, is limited due to inadequate knowledge of biobanking and concerns about sample donation. This study explores the effectiveness of different publicity methods in improving participants' willingness to donate, and assesses public motivations and concerns. It aims to identify an efficient method of improving participants' awareness of biobanking and promoting sample donation.
A structured 20-item questionnaire was formulated to evaluate participants' knowledge of and attitudes toward biobanks and sample donation. In total, 1,500 questionnaires were disseminated to three groups of 500 participants who received, respectively, picture-based promotional material, text-based promotional material, or who attended a biobank-related lecture. Of these, 945 completed questionnaires were received. All the participants completed the questionnaires twice, before and after the corresponding publicity education.
After each of the three methods of publicity based on text, pictures and a lecture, respondents' willingness to donate samples was significantly increased ( < 0.001), the lecture being more effective than the other two methods ( = 0.001). Participants with a medical background were more willing to donate biospecimens after publicity than those without medical backgrounds ( < 0.005) but had common motivations for donation including altruism and aiding medical research. The main concern hindering respondents' willingness to donate was the security of personal information.
Different types of biobank-related publicity based on text material, pictorial material and a lecture all improved respondents' willingness to donate and reduced concerns regarding sample donation. Medical background was a critical factor affecting attitudes toward sample donation after publicity. The results of this study suggest strategies that may popularize biobanks and enhance sample donation, further promoting the development of biobanks.
生物库是研究和科学进步的重要辅助手段。由于对生物库的了解不足以及对样本捐赠的担忧，公众对生物库的参与度有限，而这种参与对于生物库的发展是必要的。本研究旨在探讨不同宣传方式在提高参与者捐赠意愿方面的效果，并评估公众的动机和关注点。目的是确定一种有效的方法，以提高参与者对生物库的认识并促进样本捐赠。
设计了一份包含 20 个问题的结构式问卷，用于评估参与者对生物库和样本捐赠的知识和态度。总共向三组各 500 名参与者发放了 1500 份问卷，他们分别接受了基于图片的宣传材料、基于文本的宣传材料或参加了与生物库相关的讲座。其中，收到了 945 份完整的问卷。所有参与者在接受相应的宣传教育前后两次填写了问卷。
在基于文本、图片和讲座的三种宣传方式之后，受访者的样本捐赠意愿均显著增加（<0.001），且讲座的效果优于其他两种方法（=0.001）。在宣传后，具有医学背景的参与者比没有医学背景的参与者更愿意捐赠生物样本（<0.005），但他们的捐赠动机相同，包括利他主义和帮助医学研究。阻碍受访者捐赠意愿的主要关注点是个人信息的安全性。
基于文本材料、图片材料和讲座的不同类型的生物库相关宣传都提高了受访者的捐赠意愿，并减少了对样本捐赠的担忧。宣传后，医学背景是影响样本捐赠态度的关键因素。本研究的结果为推广生物库和促进样本捐赠提供了策略，进一步推动了生物库的发展。
