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阴茎出现前列腺特异性膜抗原正电子发射断层扫描/计算机断层扫描(PSMA-PET/CT)摄取活跃的转移性前列腺癌。

PSMA-PET/CT-avid metastatic prostate cancer to the penis.

作者信息

Mansbridge Margaret Mary, Strahan Andrew, Parker Jonathon, Rhee Handoo

机构信息

Urology, Princess Alexandra Hospital Health Service District, Woolloongabba, Queensland, Australia

Urology, Princess Alexandra Hospital Health Service District, Woolloongabba, Queensland, Australia.

出版信息

BMJ Case Rep. 2020 Mar 24;13(3):e233522. doi: 10.1136/bcr-2019-233522.

Abstract

Penile metastases from prostate cancer (PC) are rarely reported in the literature. Most commonly diagnosed due to presentation with malignant priapism and other urinary symptoms or from findings on clinical examination, prognosis has been reported to be poor. The authors outline a case of penile metastasis from advanced PC. Initially treated with neoadjuvant androgen deprivation therapy for locally advanced PC, this patient displayed upfront castrate resistance, and subsequent prostate-specific membrane antigen positron emission tomography revealed penile metastatic deposits. The patient was treated with external beam radiotherapy, and worsening urethral stricture disease resulted in the placement of a suprapubic catheter.

摘要

前列腺癌(PC)的阴茎转移在文献中鲜有报道。最常见的诊断原因是出现恶性阴茎异常勃起和其他泌尿系统症状,或临床检查发现,据报道其预后较差。作者概述了一例晚期PC阴茎转移的病例。该患者最初因局部晚期PC接受新辅助雄激素剥夺治疗,但表现出初始去势抵抗,随后的前列腺特异性膜抗原正电子发射断层扫描显示有阴茎转移灶。患者接受了外照射放疗,尿道狭窄疾病的恶化导致耻骨上导管置入。

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