Tsuchiya R, Harada N, Tsunoda T, Miyamoto T, Ura K
Second Department of Surgery, Nagasaki University School of Medicine, Japan.
Int J Pancreatol. 1988 Dec;3(6):491-6. doi: 10.1007/BF02788207.
Reports of 35 long-term more than five years survivors after resectional surgery which was performed for carcinoma of the pancreas from 1966 to 1980 were collected from major institutions in Japan and analyzed. Male to female ratio was 0.94:1 and average age was 56 years old. In 34 of the 35, the tumor was located at the head of the pancreas, 32 received pancreatoduodenectomy and two underwent total pancreatectomy. One patient with carcinoma of the tail received distal pancreatectomy. There was no correlation between the size of tumor and the postoperative prognosis. It seems that lymph node metastasis is not an obstacle to long postoperative survivals when they are removed, and also invasion to the pancreatic capsule shows no relationship to prognosis. However, there were no definite or severe invasions to the retroperitoneal tissue, nor to the portal venous system in the 35 patients at all. It is considered that invasion to the retroperitoneal tissues and to the portal venous system may be the most influential factor to the postoperative prognosis.
收集了1966年至1980年期间日本各大机构对胰腺癌患者实施切除手术后存活超过5年的35例长期存活者的报告并进行分析。男女比例为0.94:1，平均年龄为56岁。35例患者中，34例肿瘤位于胰头，32例行胰十二指肠切除术，2例行全胰切除术。1例胰尾癌患者行胰体尾切除术。肿瘤大小与术后预后无相关性。似乎淋巴结转移在切除后并非影响术后长期存活的障碍，侵犯胰腺被膜也与预后无关。然而，这35例患者均未出现明确或严重的腹膜后组织侵犯以及门静脉系统侵犯。据认为，腹膜后组织和门静脉系统侵犯可能是影响术后预后的最主要因素。
