Röhle G, Schlebusch H, Geilenkeuser W J, Kruse R
Institut für Klinische Biochemie, Universität Bonn.
J Clin Chem Clin Biochem. 1988 Jul;26(7):441-6. doi: 10.1515/cclm.1988.26.7.441.
The reliability of bilirubin analyses is especially important in cases of neonatal hyperbilirubinaemia. However, when the means of the results of external quality control surveys and the method-dependent stated values for control sera were compared with reference method values, differences of up to 10% were found. Further inaccuracy arose from interlaboratory imprecision, which showed coefficients of variation of at least 7%, and from greater or lesser interference from contamination of samples with haemoglobin. The present work investigates whether the current situation can be improved by available means.
