Department of Veterinary Surgery and Radiology, University of Ilorin, P.M.B. 1515, Ilorin, Nigeria.
Department of Veterinary Pathology, University of Ilorin, P.M.B. 1515, Ilorin, Nigeria.
J Vet Med Sci. 2020 May 30;82(5):531-535. doi: 10.1292/jvms.19-0552. Epub 2020 Mar 24.
Surgical trauma to the abdominal wall and peritoneum during celiotomy is expected to cause postoperative inflammation. However, complications after abdominal surgery are hardly detected in the early stage. Hematological analysis of blood has been considered beneficial in disease diagnosis and prognosis. This study aimed to evaluate the hematological parameters predicting peritonitis in goats and to determine the post-surgery day that hematology is significant. Six apparently healthy West African Dwarf goats were included in this study. After 2 weeks of acclimatization, blood samples were obtained daily for 3 days for hematological analyses, which served as the baseline data. The right flanks of the animals were aseptically prepared routinely for exploratory laparotomy. Restraint and anesthesia were achieved using xylazine and lignocaine using an inverted "L" block technique. Laparotomy was performed, and the incision was left for 20 min and then closed routinely. Blood samples were collected for hemogram 24 hr postoperatively and daily for 7 days. Based on the post-surgery hematology results, relative neutrophil (P=0.015) and lymphocyte (P=0.006) counts significantly increased and decreased on day 5 respectively. Significant differences were also observed for red blood cell count, hemoglobin concentration, and packed cell volume on days 5, 6, and 7 respectively. It could therefore be concluded that the diagnostic result for hematology post-laparotomy can be obtained on the fifth and sixth day.
开腹术时对腹壁和腹膜的外科创伤预计会引起术后炎症。然而，腹部手术后的并发症在早期很难被发现。血液的血液学分析被认为对疾病诊断和预后有益。本研究旨在评估预测山羊腹膜炎的血液学参数，并确定手术后血液学具有重要意义的天数。本研究纳入了 6 只明显健康的西非德系小尾寒羊。适应期 2 周后，每天采集血液样本进行 3 天的血液学分析，作为基线数据。动物的右侧腰部常规进行无菌准备，进行剖腹探查术。使用二甲噻嗪和利多卡因采用倒置"L"块技术进行约束和麻醉。进行剖腹手术，切口留置 20 分钟，然后常规关闭。术后 24 小时和术后第 7 天每天采集血液样本进行血常规检查。根据术后血液学结果，相对中性粒细胞（P=0.015）和淋巴细胞（P=0.006）计数分别在第 5 天和第 5 天显著增加和减少。红细胞计数、血红蛋白浓度和红细胞压积在第 5、6 和 7 天也有显著差异。因此，可以得出结论，剖腹手术后的血液学诊断结果可以在第 5 天和第 6 天获得。
