Anh Bui Thi Van, Dat Nguyen Thai, Vu Anh Tuan, Hieu Nguyen Trung, Quyet Do, Thai Than Van, Nga Vu Thi, Dinh Toi Chu, Bac Nguyen Duy
Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
Hanoi Medical College, Hanoi, Vietnam.
Open Access Maced J Med Sci. 2019 Dec 20;7(24):4278-4282. doi: 10.3889/oamjms.2019.374. eCollection 2019 Dec 30.
Glaucoma is a common cause of blindness in the world as well as in Vietnam. It is treated by many different methods but trabeculectomy is still the most popular and highly effective surgical method to treat this condition.
To analyze the status of 5 years filtering blebs following trabeculectomy and to explore multiple factors associated with filtering blebs.
This is a retrospective, cross-sectional descriptive study. Eyes had been performed trabeculectomy for 5 years were included in these results. The filtering blebs were assessed using slit lamp and OCT. the OCT captured bleb area to evaluate fluid subconjunctival spaces, thickness and height of bleb and to evaluate the related factors.
A group of 106 primary glaucoma eyes of 97 patients (88 patients with 1 eye, 9 patients 2 eyes) had been performed trabeculectomy for 5 years were taken OCT anterior image. The proportion of female patients is 1.5 times that of male patients. IOP was controlled with or without topical medication in all eyes. The filtering bleb had a high echo reflection, which accounted for 42.5%, the average echo reflection was 38.6%, the low echo reflection response of 18.9%. 66% of the eyes had the aqueous space under the conjunctiva, 65.1% have the aqueous space under sclera flap, the average height of the bleb on OCT was 0.4 mm ± 0.3 mm. Young patients often have a higher rate of bleb fibrosis and loss of function than older patients.
OCT is capable of assessing the function of bleb. After 5 years of trabeculectomy, on the OCT image, most cases of blebs are maintaining drainage function.
青光眼是全球以及越南失明的常见原因。其治疗方法多样，但小梁切除术仍是治疗该疾病最常用且高效的手术方法。
分析小梁切除术后5年滤过泡的状况，并探究与滤过泡相关的多种因素。
这是一项回顾性横断面描述性研究。纳入接受小梁切除术5年的眼睛的相关结果。使用裂隙灯和光学相干断层扫描（OCT）评估滤过泡。OCT采集滤过泡区域图像以评估结膜下液性间隙、滤过泡的厚度和高度，并评估相关因素。
对97例患者的106只原发性青光眼患眼（88例单眼，9例双眼）进行了小梁切除术，术后5年拍摄了OCT眼前节图像。女性患者比例是男性患者的1.5倍。所有患眼眼压通过或未通过局部用药均得到控制。滤过泡高回声反射占42.5%，平均回声反射占38.6%，低回声反射占18.9%。66%的患眼结膜下有房水间隙，65.1%的患眼巩膜瓣下有房水间隙，OCT上滤过泡平均高度为0.4毫米±0.3毫米。年轻患者滤过泡纤维化和功能丧失的发生率通常高于老年患者。
OCT能够评估滤过泡功能。小梁切除术后5年，在OCT图像上，大多数滤过泡病例仍保持引流功能。
