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越南患者圆锥角膜的穿透性角膜移植术

Penetrating Keratoplasty for Keratoconus in Vietnamese Patients.

作者信息

Cung Le Xuan, Nga Duong Mai, Ngan Nguyen Dinh, Hiep Nguyen Xuan, Quyet Do, Thai Than Van, Nga Vu Thi, Dinh Toi Chu, Bac Nguyen Duy

机构信息

Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.

Vietnam Military Medical University (VMMU), Hanoi, Vietnam.

出版信息

Open Access Maced J Med Sci. 2019 Dec 20;7(24):4287-4291. doi: 10.3889/oamjms.2019.376. eCollection 2019 Dec 30.

DOI:10.3889/oamjms.2019.376
PMID:32215079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7084045/
Abstract

BACKGROUND

Keratoconus is an ectatic corneal disorder that can impair the visual acuity. Up to now, penetrating keratoplasty (PK) remains the most common surgical procedure to treat severe keratoconus. In Vietnam, most keratoconus patients come to visit doctor at severe stage and were treated by PK, so we conduct this study.

AIM

To evaluate the results of PK for keratoconus in Vietnamese patients.

METHODS

This was a retrospective study of 31 eyes with keratoconus who underwent PK in VNIO from January 2005 to December 2014.

RESULTS

The average visual acuity was 0.86 ± 0.37 logMAR (20/145). In the group of patients without amblyopia, best spectacle-corrected visual acuity of 20/60 or better was recorded in 75.9% of eyes and 93.1% of eyes achieved a best corrected visual acuity with hard contact lenses of 20/40 or better. Mean postoperative corneal power was 43.8 ± 4.5D. Mean corneal astigmatism was 5.9 ± 2.7D. 94.6% of grafts remained clear. Posterior subcapsular cataract developed in 22.6% of eyes. Graft rejection was recognized in 12.9% of eyes.

CONCLUSION

PK is an effective procedure with high rate of graft survival for keratoconus patients. However, patients should be aware of the necessary of optical correction to gain the best VA after surgery.

摘要

背景

圆锥角膜是一种可损害视力的角膜扩张性疾病。到目前为止,穿透性角膜移植术(PK)仍然是治疗严重圆锥角膜最常见的外科手术。在越南,大多数圆锥角膜患者在疾病严重阶段才前来就医并接受PK治疗,因此我们开展了这项研究。

目的

评估越南患者圆锥角膜PK手术的效果。

方法

这是一项对2005年1月至2014年12月在越南国家眼科研究所接受PK手术的31例圆锥角膜患者的回顾性研究。

结果

平均视力为0.86±0.37 logMAR(20/145)。在无弱视的患者组中,75.9%的患眼最佳矫正视力达到20/60或更好,93.1%的患眼使用硬性角膜接触镜矫正后最佳视力达到20/40或更好。术后平均角膜屈光力为43.8±4.5D。平均角膜散光为5.9±2.7D。94.6%的移植片保持透明。22.6%的患眼发生后囊下白内障。12.9%的患眼出现移植片排斥反应。

结论

PK手术对圆锥角膜患者是一种有效的手术,移植片存活率高。然而,患者应意识到术后进行光学矫正以获得最佳视力的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48a/7084045/5be4963689ba/OAMJMS-7-4287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48a/7084045/38686eb9bbfc/OAMJMS-7-4287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48a/7084045/5be4963689ba/OAMJMS-7-4287-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48a/7084045/38686eb9bbfc/OAMJMS-7-4287-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d48a/7084045/5be4963689ba/OAMJMS-7-4287-g002.jpg

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本文引用的文献

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Long-term outcomes of deep anterior lamellar keratoplasty versus penetrating keratoplasty in Australian keratoconus patients.澳大利亚圆锥角膜患者深板层角膜移植与穿透性角膜移植的长期疗效比较。
Cornea. 2014 Jan;33(1):6-9. doi: 10.1097/ICO.0b013e3182a9fbfd.
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Keratoconus: current perspectives.圆锥角膜:当前观点
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Indications and outcomes of corneal transplantation in geriatric patients.老年患者角膜移植的适应证和结果。
Am J Ophthalmol. 2013 Sep;156(3):600-607.e2. doi: 10.1016/j.ajo.2013.04.034. Epub 2013 Jun 13.
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Penetrating keratoplasty for keratoconus: visual and graft survival outcomes.圆锥角膜穿透性角膜移植术:视力及植片存活结果
Int J Health Sci (Qassim). 2013 Jan;7(1):67-74. doi: 10.12816/0006023.
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The Auckland keratoconus study: identifying predictors of acute corneal hydrops in keratoconus.奥克兰圆锥角膜研究:确定圆锥角膜急性角膜水肿的预测因素。
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Keratoconus patients at Jordan University Hospital: a descriptive study.约旦大学医院的圆锥角膜患者:一项描述性研究。
Clin Ophthalmol. 2012;6:1895-9. doi: 10.2147/OPTH.S38287. Epub 2012 Nov 16.
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